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Bolz, M; Menapace, R; Findl, O; Sacu, S; Buehl, W; Wirtitsch, M; Leydolt, C; Kriechbaum, K.
Effect of anterior capsule polishing on the posterior capsule opacification-inhibiting properties of a sharp-edged, 3-piece, silicone intraocular lens: three- and 5-year results of a randomized trial.
J Cataract Refract Surg. 2006; 32(9): 1513-1520.
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Authors Med Uni Graz:
Wirtitsch Matthias

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PURPOSE: To evaluate the long-term effects of anterior capsule polishing on regeneratory posterior capsule opacification (PCO), anterior capsule opacification (ACO), and fibrotic PCO with a silicone intraocular lens (IOL) with sharp optic edges. SETTING: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. METHODS: This prospective bilateral randomized patient- and examiner-masked clinical trial comprised 130 eyes of 65 patients with bilateral age-related cataract. All eyes had implantation of a 3-piece silicone IOL with a truncated, sharp-edged optic (CeeOn Edge 911A, Advanced Medical Optics). In 1 eye, the anterior capsule was extensively polished using an aspiration curette after phacoemulsification and cortex aspiration. Regenerative PCO was quantified objectively, while ACO and fibrotic PCO were graded subjectively 1, 2, 3, and 5 years postoperatively. RESULTS: The mean ACO score was significantly lower in the eyes in which the anterior capsule had been polished (1 year, P<.02; 2 years, P<.03; 3 years, P<.01; 5 years, P<.01). The mean difference in regeneratory PCO and fibrotic PCO scores between the 2 groups was not statistically significant. CONCLUSIONS: Three years after cataract surgery, eyes in which the anterior capsule had been polished had significantly less ACO. However, polishing did not lower PCO intensity when a sharp-edged CeeOn 911A IOL was implanted in the bag. Although results indicate that anterior capsule polishing may enhance the development of regeneratory PCO, this trend did not reach statistical significance.
Find related publications in this database (using NLM MeSH Indexing)
Cataract - etiology
Double-Blind Method - etiology
Epithelial Cells - pathology
Fibrosis - pathology
Follow-Up Studies - pathology
Humans - pathology
Lens Capsule, Crystalline - pathology
Lens Implantation, Intraocular - pathology
Lenses, Intraocular - adverse effects
Phacoemulsification - adverse effects
Prospective Studies - adverse effects
Prosthesis Design - adverse effects
Silicone Elastomers - adverse effects
Suction - methods

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