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Herrero, D; Einspieler, C; Panvequio Aizawa, CY; Mutlu, A; Yang, H; Nogolová, A; Pansy, J; Nielsen-Saines, K; Marschik, PB; GenGM Study Group.
The motor repertoire in 3- to 5-month old infants with Down syndrome.
Res Dev Disabil. 2017; 67(7):1-8 [OPEN ACCESS]
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Authors Med Uni Graz:
Einspieler Christa
Marschik Peter
Pansy Jasmin
Study Group Members Med Uni Graz:
Krieber-Tomantschger Iris
Krieber-Tomantschger Magdalena
Marschik Dajie
Scheuchenegger Anna Birgitta
Urlesberger Berndt
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Abstract:
Even though Down syndrome is the most common chromosomal cause of intellectual disability, studies on early development are scarce. To describe movements and postures in 3- to 5-month-old infants with Down syndrome and assess the relation between pre- and perinatal risk factors and the eventual motor performance. Exploratory study; 47 infants with Down syndrome (26 males, 27 infants born preterm, 22 infants with congenital heart disease) were videoed at 10-19 weeks post-term (median=14 weeks). We assessed their Motor Optimality Score (MOS) based on postures and movements (including fidgety movements) and compared it to that of 47 infants later diagnosed with cerebral palsy and 47 infants with a normal neurological outcome, matched for gestational and recording ages. The MOS (median=13, range 10-28) was significantly lower than in infants with a normal neurological outcome (median=26), but higher than in infants later diagnosed with cerebral palsy (median=6). Fourteen infants with Down syndrome showed normal fidgety movements, 13 no fidgety movements, and 20 exaggerated, too fast or too slow fidgety movements. A lack of movements to the midline and several atypical postures were observed. Neither preterm birth nor congenital heart disease was related to aberrant fidgety movements or reduced MOS. The heterogeneity in fidgety movements and MOS add to an understanding of the large variability of the early phenotype of Down syndrome. Studies on the predictive values of the early spontaneous motor repertoire, especially for the cognitive outcome, are warranted. The significance of this exploratory study lies in its minute description of the motor repertoire of infants with Down syndrome aged 3-5 months. Thirty percent of infants with Down syndrome showed age-specific normal fidgety movements. The rate of abnormal fidgety movements (large amplitude, high/slow speed) or a lack of fidgety movements was exceedingly high. The motor optimality score of infants with Down syndrome was lower than in infants with normal neurological outcome but higher than in infants who were later diagnosed with cerebral palsy. Neither preterm birth nor congenital heart disease were related to the motor performance at 3-5 months. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.
Find related publications in this database (using NLM MeSH Indexing)
Disability Evaluation -
Down Syndrome - diagnosis
Down Syndrome - physiopathology
Female -
Gestational Age -
Humans -
Infant -
Male -
Motor Activity - physiology
Movement - physiology
Neurologic Examination - methods
Patient Outcome Assessment -
Posture - physiology
Psychomotor Performance -
Risk Factors -
Statistics as Topic -

Find related publications in this database (Keywords)
Down syndrome
Fidgety movements
General movements
Infant
Motor optimality score
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