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Selected Publication:

SHR Neuro Cancer Cardio Lipid Metab Microb

Jahn, SW; Jost, PJ.
Challenges in integrating molecular profiles into clinical cancer care
MEMO-MAG EUR MED ONC. 2022; Doi: 10.1007/s12254-022-00838-1
Web of Science FullText FullText_MUG

 

Leading authors Med Uni Graz
Jahn Stephan
Jost Philipp
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Abstract:
Profiling of malignancies with next-generation sequencing (NGS) is now routine in clinical practice. While many cases of approved targeted therapies are straightforward based on well-characterized alterations, applying large NGS multigene panels to therapeutic use is frequently challenging. In this article, variant interpretation, therapy matching, and final treatment selection challenges are discussed.

Find related publications in this database (Keywords)
Next-generation sequencing application
Variant annotation
Therapy matching
Challenges
Clinical tiering
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