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Koeppl, C; Findl, O; Menapace, R; Kriechbaum, K; Wirtitsch, M; Buehl, W; Sacu, S; Drexler, W.
Pilocarpine-induced shift of an accommodating intraocular lens: AT-45 Crystalens.
J Cataract Refract Surg. 2005; 31(7):1290-1297
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Authors Med Uni Graz:
Wirtitsch Matthias
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Abstract:
PURPOSE: To measure the shift of an accommodating plate-haptic intraocular lens (IOL) along the visual axis induced by ciliary muscle contraction after application of pilocarpine. SETTING: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. METHODS: Fifty-four eyes of 28 patients with age-related cataract comprised this prospective study. Each patient received an AT-45 silicone accommodating IOL (Crystalens, Eyeonics Corp.) after standardized cataract surgery. In a subgroup of 24 eyes, capsular bag fibrosis was reduced by extensive polishing of the anterior capsule with a slit cannula. Assessment included measurements of anterior chamber depth, assessed with partial coherence interferometry, before and after application of pilocarpine 2% and evaluation of near visual acuity 1 month and 3 months postoperatively. RESULTS: A slight backward shift of the IOL of 151 mum in the nonpolished group (P < .001) and 122 mum in the polished group (P < .005) could be detected after application of pilocarpine. Polishing the capsule did not influence IOL shift. The median near visual acuity with distance correction 1 month and 3 months postoperatively was J5 and J4, respectively, in the nonpolished group and J6 at both times in the polished group. CONCLUSIONS: Pilocarpine induced a counterproductive active backward shift of the AT-45 IOL. Polishing of the capsular bag had no impact on accommodative ability. The reading performance of patients with the AT-45 IOL patients at 1 and 3 months was not significantly different from that of with a standard IOL under similar testing methods.
Find related publications in this database (using NLM MeSH Indexing)
Accommodation, Ocular - drug effects
Aged - drug effects
Aged, 80 and over - drug effects
Ciliary Body - drug effects
Foreign-Body Migration - etiology
Humans - etiology
Lens Implantation, Intraocular - etiology
Lenses, Intraocular - etiology
Middle Aged - etiology
Miotics - adverse effects
Muscle Contraction - drug effects
Muscle, Smooth - drug effects
Phacoemulsification - drug effects
Pilocarpine - adverse effects
Prospective Studies - adverse effects
Prosthesis Design - adverse effects

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