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SHR Neuro Cancer Cardio Lipid Metab Microb

Toth, GG; Achim, A; Kafka, M; Wu, X; Lunardi, M; Biswas, S; Shahzad, A; Thury, A; Ruzsa, Z; Johnson, TW; Wijns, W.
Bench test and in vivo evaluation of longitudinal stent deformation during proximal optimisation.
EuroIntervention. 2022; 18(1):83-90 Doi: 10.4244/EIJ-D-21-00824 [OPEN ACCESS]
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Leading authors Med Uni Graz: Toth-Gayor Gabor
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Abstract:: BACKGROUND: While radial stent deformation has been thoroughly investigated, data on longitudinal deformation are scarce. AIMS: The aim of the study was to describe longitudinal stent deformation associated with the proximal optimisation technique (POT). METHODS: Longitudinal stent deformation was assessed by bench testing and by clinical evaluation. Bench testing was performed in silicone models using 3.00 (n=15) and 3.50 mm (n=14) stent platforms. After deployment, stents were sequentially post-dilated in the proximal main branch up to 5.50 mm, in increments of 0.50 mm, in order to simulate a spectrum of overexpansion. Stent length was redefined by optical coherence tomography (OCT) after each step. Clinical data were collected retrospectively from OCT-guided bifurcation percutaneous coronary intervention cases. RESULTS: In bench tests, POT has led to significant stent elongation in all cases. The magnitude of elongation was comparable between the 3.00 and the 3.50 mm stent platforms, with 0.86±0.74 mm vs 0.86±0.73 mm, respectively (p=0.71), per 0.5 mm overexpansion. For 3.00 mm stent platforms, maximal elongation was 4.31±1.47 mm after up to 5.5 mm overexpansion. For 3.50 mm platforms, maximal elongation was 2.87±0.94 mm after up to 5.5 mm overexpansion. Thirty-six clinical cases were analysed, of which 22 (61%) were performed in the distal left main. Post-dilation was performed with 0.98±0.36 mm absolute overexpansion, resulting in 2.22±1.35 mm elongation, as compared to nominal stent length. CONCLUSIONS: Overexpansion by POT results in proximal stent elongation. This has to be considered once the stent length is selected and the stent is positioned, especially in the left main stem, where proximal overexpansion is marked and accurate ostial landing is critical.
Find related publications in this database (using NLM MeSH Indexing): Angioplasty, Balloon, Coronary - methods; Coronary Angiography - administration & dosage; Coronary Vessels - diagnostic imaging, surgery; Humans - administration & dosage; Percutaneous Coronary Intervention - administration & dosage; Prosthesis Design - administration & dosage; Retrospective Studies - administration & dosage; Stents - administration & dosage; Tomography, Optical Coherence - administration & dosage
Find related publications in this database (Keywords): bifurcation; drug-eluting stent; left main