Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Heyndrickx, GR; Tóth, GG.
The FAME Trials: Impact on Clinical Decision Making.
Interv Cardiol. 2016; 11(2):116-119
Doi: 10.15420/icr.2016:14:3
[OPEN ACCESS]
PubMed
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- Co-authors Med Uni Graz
- Toth-Gayor Gabor
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- Abstract:
- Careful and stepwise evaluation of the fractional flow reserve (FFR) index has been performed over the years, culminating in the landmark Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (FAME) and Fractional Flow Reserve-Guided Percutaneous Coronary Intervention Plus Optimal Medical Treatment Versus Optimal Medical Treatment Alone in Patients with Stable Coronary Artery Disease (FAME II) trials. Findings from these studies demonstrated unequivocally the overall inadequacy of angiography versus FFR to correctly assess stenosis severity. Thus, proof of concept and clinical applicability was established beyond debate and will be discussed here.