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SHR Neuro Cancer Cardio Lipid Metab Microb

Smolle, M; Uranitsch, S; Gerger, A; Pichler, M; Haybaeck, J.
Current status of long non-coding RNAs in human cancer with specific focus on colorectal cancer.
Int J Mol Sci. 2014; 15(8):13993-14013 Doi: 10.3390/ijms150813993 [OPEN ACCESS]
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Leading authors Med Uni Graz
Haybäck Johannes
Smolle Maria Anna
Co-authors Med Uni Graz
Gerger Armin
Pichler Martin

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The latest investigations of long non-coding RNAs (lncRNAs) have revealed their important role in human cancers. LncRNAs are larger than 200 nucleotides in length and fulfill their cellular purpose without being translated into proteins. Though the molecular functions of some lncRNAs have been elucidated, there is still a high number of lncRNAs with unknown or controversial functions. In this review, we provide an overview of different lncRNAs and their role in human cancers. In particular, we emphasize their importance in tumorigenesis of colorectal cancer, the third most common cancer worldwide.
Find related publications in this database (using NLM MeSH Indexing)
Biomarkers, Tumor - metabolism
Carcinoembryonic Antigen - metabolism
Colorectal Neoplasms - drug therapy
Humans -
Neoplasm Staging -
Neoplasms - genetics
RNA, Long Noncoding - metabolism

Find related publications in this database (Keywords)
colorectal cancer
molecular tumor pathogenesis
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