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Suppan, E; Pichler, G; Binder-Heschl, C; Schwaberger, B; Urlesberger, B.
Three Physiological Components That Influence Regional Cerebral Tissue Oxygen Saturation.
Front Pediatr. 2022; 10: 913223 Doi: 10.3389/fped.2022.913223 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Leading authors Med Uni Graz
Suppan Ena
Urlesberger Berndt
Co-authors Med Uni Graz
Binder-Heschl Corinna
Pichler Gerhard
Schwaberger Bernhard Christian
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Abstract:
Near-infrared spectroscopy (NIRS) measurement of regional cerebral tissue oxygen saturation (rcStO2) has become a topic of high interest in neonatology. Multiple studies have demonstrated that rcStO2 measurements are feasible in the delivery room during immediate transition and resuscitation as well as after admission to the neonatal intensive care unit. Reference ranges for different gestational ages, modes of delivery, and devices have already been published. RcStO2 reflects a mixed tissue saturation, composed of arterial (A), venous (V), and capillary signals, derived from small vessels within the measurement compartment. The A:V signal ratio fluctuates based on changes in oxygen delivery and oxygen consumption, which enables a reliable trend monitoring of the balance between these two parameters. While the increasing research evidence supports its use, the interpretation of the absolute values of and trends in rcStO2 is still challenging, which halts its routine use in the delivery room and at the bedside. To visualize the influencing factors and improve the understanding of rcStO2 values, we have created a flowchart, which focuses on the three major physiological components that affect rcStO2: oxygen content, circulation, and oxygen extraction. Each of these has its defining parameters, which are discussed in detail in each section.

Find related publications in this database (Keywords)
regional cerebral tissue oxygen saturation
near-infrared spectroscopy
oxygen content
circulation
oxygen extraction
neonate
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