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SHR Neuro Krebs Kardio Lipid

Pfurtscheller, K; Senning, B; Bernhard, H; Novak, M; Zobel, G; Plecko, B; Muntean, W.
Malignant stroke in an adolescent with a homozygous MTHFR 677CT mutation and intake of hormonal contraceptives
HAMOSTASEOLOGIE. 2009; 29: S84-S86. (- Case Report)
Web of Science PubMed


Autor/innen der Med Uni Graz:
Bernhard Heike
Muntean Eugen
Novak Michael
Pfurtscheller Klaus
Plecko Barbara
Zobel Gerfried

Dimensions Citations:

Plum Analytics:
Severe stroke in children and adolescents with its devastating long term consequences remains a rare disorder with many open questions. Beside the well known risk factors such as infection or congenital and acquired heart disease, coagulation disorders have to be considered in the differential work up of the underlying aetiology. Here we report the case of an adolescent with a homozygote MTHFR 677CT mutation suffering a malignant stroke shortly after the start of oral contraceptives. Since prevention seems easily feasible, general screening for MTHFR mutations might be worthwhile in women before starting oral contraceptives.
Find related publications in this database (using NLM MeSH Indexing)
Adolescent -
Contraceptives, Oral, Hormonal - adverse effects
Fatal Outcome -
Female -
Homocysteine - blood
Humans -
Infarction, Middle Cerebral Artery - chemically induced
Infarction, Middle Cerebral Artery - enzymology
Infarction, Middle Cerebral Artery - genetics
Magnetic Resonance Imaging -
Methylenetetrahydrofolate Reductase (NADPH2) - genetics
Mutation -

Find related publications in this database (Keywords)
methylenetetrahydrofolate reductase
hormonal contraceptives
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