Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Gewählte Publikation:

Lahousen, M.
Predictive value of a tumor marker combination for the monitoring of ovarian cancer
WIEN KLIN WOCHENSCHR. 1986; 98(10): 319-325.
Web of Science PubMed

 

Autor/innen der Med Uni Graz:
Lahousen Manfred
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Abstract:
The tumour markers carcinoembryonic antigen (CEA), ferritin, cancer antigen 125 (CA 125) and tissue polypeptide antigen (TPA) were measured by radioimmunoassay in sera from 80 patients with ovarian cancer pre-operatively, postoperatively, during cytostatic chemotherapy and on follow up. Discriminant analysis was applied to obtain retrospective classification of 60 patients into a group showing a favourable course of the disease (no recurrence, tumour regression) and into a group with an unfavourable course (recurrence, progression of the tumour). The classification was based on the introduction of the Cutting Score. By means of this bio-mathematical model it was possible to make at least a short-term prognostic statement in a further 20 patients. It is suggested that invasive diagnostic procedures may not be required in patients who are found to have normal tumour marker levels.
Find related publications in this database (using NLM MeSH Indexing)
Antigens, Neoplasm - analysis
Antigens, Tumor-Associated, Carbohydrate - analysis
Carcinoembryonic Antigen - analysis
Combined Modality Therapy - analysis
Female - analysis
Ferritins - blood
Humans - blood
Lymphatic Metastasis - blood
Neoplasm Recurrence, Local - diagnosis
Neoplasm Staging - diagnosis
Ovarian Neoplasms - diagnosis
Peptides - analysis
Prognosis - analysis
Radioimmunoassay - analysis
Tissue Polypeptide Antigen - analysis

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