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Gewählte Publikation:

Bauernhofer, T; Eibl, M; Ploner, F; Kuss, I; Pfeifer, J; Sill, H; Samonigg, H.
Acute pseudo-obstruction of the small intestine following high-dose chemotherapy and stem cell support.
Onkologie. 2003; 26(4):344-346 Doi: 10.1159/000072093 (- Case Report)
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Führende Autor*innen der Med Uni Graz
Bauernhofer Thomas
Co-Autor*innen der Med Uni Graz
Eibl Margit
Pfeifer Johann
Ploner Ferdinand
Samonigg Hellmut
Sill Heinz

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BACKGROUND: Acute intestinal pseudo-obstruction is a potentially life-threatening disease which is characterized by massive dilation of the colon or small intestine without mechanical obstruction and may develop after surgery or severe illness. PATIENTS AND METHODS: We report 2 cases in which acute small intestinal pseudo-obstruction occurred after high-dose chemotherapy and autologous stem cell support. In 1 patient explorative abdominal laparoscopy was performed to rule out mechanical ileus. However, after having initiated treatment with acetylcholinesterase inhibitors a prompt small intestinal decompression was observed in both patients. CONCLUSIONS: Acetylcholinesterase inhibitors should be considered as an early conservative intervention in the treatment of acute intestinal pseudo-obstruction to avoid surgery of patients undergoing high-dose chemotherapy with autologous stem cell support.
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Antineoplastic Combined Chemotherapy Protocols - adverse effects
Breast Neoplasms - drug therapy
Carcinoma, Ductal - drug therapy
Chemotherapy, Adjuvant - adverse effects
Combined Modality Therapy - adverse effects
Dose-Response Relationship, Drug - adverse effects
Hematopoietic Stem Cell Transplantation - adverse effects
Humans - adverse effects
Intestinal Pseudo-Obstruction - chemically induced
Intestine, Small - chemically induced
Male - chemically induced
Mastectomy, Segmental - chemically induced
Middle Aged - chemically induced
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Find related publications in this database (Keywords)
acute intestinal pseudo-obstruction
high-dose chemotherapy
autologous peripheral blood progenitor cell support
acetylcholinesterase inhibitors
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