Gewählte Publikation:
Bauernhofer, T; Eibl, M; Ploner, F; Kuss, I; Pfeifer, J; Sill, H; Samonigg, H.
Acute pseudo-obstruction of the small intestine following high-dose chemotherapy and stem cell support.
Onkologie. 2003; 26(4):344-346
Doi: 10.1159/000072093
(- Case Report)
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
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Bauernhofer Thomas
- Co-Autor*innen der Med Uni Graz
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Eibl Margit
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Pfeifer Johann
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Ploner Ferdinand
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Samonigg Hellmut
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Sill Heinz
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- Abstract:
- BACKGROUND: Acute intestinal pseudo-obstruction is a potentially life-threatening disease which is characterized by massive dilation of the colon or small intestine without mechanical obstruction and may develop after surgery or severe illness. PATIENTS AND METHODS: We report 2 cases in which acute small intestinal pseudo-obstruction occurred after high-dose chemotherapy and autologous stem cell support. In 1 patient explorative abdominal laparoscopy was performed to rule out mechanical ileus. However, after having initiated treatment with acetylcholinesterase inhibitors a prompt small intestinal decompression was observed in both patients. CONCLUSIONS: Acetylcholinesterase inhibitors should be considered as an early conservative intervention in the treatment of acute intestinal pseudo-obstruction to avoid surgery of patients undergoing high-dose chemotherapy with autologous stem cell support.
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Adult -
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Antineoplastic Combined Chemotherapy Protocols - adverse effects
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Breast Neoplasms - drug therapy
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Carcinoma, Ductal - drug therapy
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Chemotherapy, Adjuvant - adverse effects
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Combined Modality Therapy - adverse effects
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Dose-Response Relationship, Drug - adverse effects
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Hematopoietic Stem Cell Transplantation - adverse effects
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Humans - adverse effects
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Intestinal Pseudo-Obstruction - chemically induced
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Intestine, Small - chemically induced
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Male - chemically induced
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Mastectomy, Segmental - chemically induced
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Middle Aged - chemically induced
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Neoplasms, Germ Cell and Embryonal - drug therapy
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Testicular Neoplasms - drug therapy
- Find related publications in this database (Keywords)
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acute intestinal pseudo-obstruction
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high-dose chemotherapy
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autologous peripheral blood progenitor cell support
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acetylcholinesterase inhibitors