Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Wehrschütz, M; Stöger, H; Ploner, F; Hofmann, G; Wolf, G; Höfler, G; Krippl, P; Samonigg, H.
Seminoma metastases mimicking primary pancreatic cancer.
Onkologie. 2002; 25(4):371-373
Doi: 10.1159/000066057
(- Case Report)
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Wehrschütz Martin
- Co-Autor*innen der Med Uni Graz
- Höfler Gerald
- Hofmann Guenter
- Krippl Peter
- Ploner Ferdinand
- Samonigg Hellmut
- Stöger Herbert
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- Abstract:
- A case of seminoma clinical stage III, arising from the right testis and mimicking a primary pancreatic malignancy is reported. A 57-year-old male patient presented with obstructive jaundice. He suffered from recurrent abdominal pain and significant weight loss over the past 4 months. Abdominal CT scan showed a tumor in the head of the pancreas and multiple pathologically enlarged peripancreatic lymph nodes. In the laboratory findings there were signs of cholestasis and infection. A laparoscopic biopsy out of a suspicious lesion of the head of the pancreas and a surrounding lymph node was done. Histopathological examination reported metastasis of seminoma in a lymph node. Further laboratory findings showed an elevation of the human placental alkaline phosphatase (HPLAP) and urological examination revealed a suspect right testis. The patient underwent castration of the right testis and histopathological examination confirmed a seminoma. 4 cycles of chemotherapy including cisplatinum, etoposide and bleomycin led into complete response that is still ongoing. This case shows a seminoma with metastases at retroperitoneal site, mimicking a primary pancreatic neoplasm. It provides an example of the possibility of an uncommon clinical appearance of seminoma metastases and again underlines the importance of exact radiological and histopathological examination to distinguish between curable and incurable tumor. Copyright 2002 S. Karger GmbH, Freiburg
- Find related publications in this database (using NLM MeSH Indexing)
- Biopsy -
- Chemotherapy, Adjuvant -
- Combined Modality Therapy -
- Diagnosis, Differential -
- Follow-Up Studies -
- Humans -
- Lymph Nodes - pathology
- Lymphatic Metastasis -
- Male -
- Middle Aged -
- Pancreas - pathology
- Pancreatic Neoplasms - diagnosis
- Pancreatic Neoplasms - drug therapy
- Pancreatic Neoplasms - pathology
- Pancreatic Neoplasms - secondary
- Pancreatic Neoplasms - surgery
- Seminoma - diagnosis
- Seminoma - drug therapy
- Seminoma - pathology
- Seminoma - secondary
- Seminoma - surgery
- Testicular Neoplasms - diagnosis
- Testicular Neoplasms - drug therapy
- Testicular Neoplasms - pathology
- Testicular Neoplasms - surgery
- Tomography, X-Ray Computed -
- Find related publications in this database (Keywords)
- metastatic seminoma
- extra gonadal germ cell tumor
- pancreatic cancer