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Gewählte Publikation:

Wehrschütz, M; Stöger, H; Ploner, F; Hofmann, G; Wolf, G; Höfler, G; Krippl, P; Samonigg, H.
Seminoma metastases mimicking primary pancreatic cancer.
Onkologie. 2002; 25(4):371-373 Doi: 10.1159/000066057 (- Case Report)
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Führende Autor*innen der Med Uni Graz
Wehrschütz Martin
Co-Autor*innen der Med Uni Graz
Höfler Gerald
Hofmann Guenter
Krippl Peter
Ploner Ferdinand
Samonigg Hellmut
Stöger Herbert

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A case of seminoma clinical stage III, arising from the right testis and mimicking a primary pancreatic malignancy is reported. A 57-year-old male patient presented with obstructive jaundice. He suffered from recurrent abdominal pain and significant weight loss over the past 4 months. Abdominal CT scan showed a tumor in the head of the pancreas and multiple pathologically enlarged peripancreatic lymph nodes. In the laboratory findings there were signs of cholestasis and infection. A laparoscopic biopsy out of a suspicious lesion of the head of the pancreas and a surrounding lymph node was done. Histopathological examination reported metastasis of seminoma in a lymph node. Further laboratory findings showed an elevation of the human placental alkaline phosphatase (HPLAP) and urological examination revealed a suspect right testis. The patient underwent castration of the right testis and histopathological examination confirmed a seminoma. 4 cycles of chemotherapy including cisplatinum, etoposide and bleomycin led into complete response that is still ongoing. This case shows a seminoma with metastases at retroperitoneal site, mimicking a primary pancreatic neoplasm. It provides an example of the possibility of an uncommon clinical appearance of seminoma metastases and again underlines the importance of exact radiological and histopathological examination to distinguish between curable and incurable tumor. Copyright 2002 S. Karger GmbH, Freiburg
Find related publications in this database (using NLM MeSH Indexing)
Biopsy -
Chemotherapy, Adjuvant -
Combined Modality Therapy -
Diagnosis, Differential -
Follow-Up Studies -
Humans -
Lymph Nodes - pathology
Lymphatic Metastasis -
Male -
Middle Aged -
Pancreas - pathology
Pancreatic Neoplasms - diagnosis
Pancreatic Neoplasms - drug therapy
Pancreatic Neoplasms - pathology
Pancreatic Neoplasms - secondary
Pancreatic Neoplasms - surgery
Seminoma - diagnosis
Seminoma - drug therapy
Seminoma - pathology
Seminoma - secondary
Seminoma - surgery
Testicular Neoplasms - diagnosis
Testicular Neoplasms - drug therapy
Testicular Neoplasms - pathology
Testicular Neoplasms - surgery
Tomography, X-Ray Computed -

Find related publications in this database (Keywords)
metastatic seminoma
extra gonadal germ cell tumor
pancreatic cancer
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