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Gewählte Publikation:

Ferrara, G; Argenziano, G; Zgavec, B; Bartenjev, I; Staibano, S; De Rosa, G; Soyer, HP.
Compound blue nevus: a reappraisal of superficial blue nevus with prominent intraepidermal dendritic melanocytes with emphasis on dermoscopic and histopathologic features.
J AMER ACAD DERMATOL 2002 46: 85-89. (- Case Report)
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Autor/innen der Med Uni Graz:
Soyer Hans Peter
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Abstract:
We describe 5 cases of "compound blue nevus" (CBN) ("superficial blue nevus with prominent intraepidermal dendritic melanocytes," "Kamino nevus"). Dermoscopically in 2 of 4 cases the bluish pigmentation characteristic of blue nevi was centrally replaced by a black lamella, with black dots and brown globules also observed in one case, thus revealing a structural asymmetry suggestive of melanoma. Histopathologically, pigmented parakeratosis was the underlying histopathologic finding of black lamella and dots/globules. Immunohistochemistry highlighted the unique histopathologic feature of CBN, namely, single dendritic melanocytes at the dermoepidermal junction with striking intraepidermal prolongations. Our findings confirm that CBN is a distinctive variant of blue nevus that may mimic cutaneous melanoma both clinically and dermoscopically.
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Adolescent -
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Arm -
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Dendritic Cells - pathology
Diagnosis, Differential - pathology
Female - pathology
Humans - pathology
Immunohistochemistry - pathology
Male - pathology
Melanocytes - pathology
Melanoma - pathology
Microscopy - pathology
Neck - pathology
Nevus, Blue - pathology
Skin Neoplasms - pathology
Thorax - pathology

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