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Gewählte Publikation:

Hinghofer-Szalkay, HG; Sauseng-Fellegger, G; Greenleaf, JE.
Plasma volume with alternative tilting: effect of fluid ingestion.
J Appl Physiol. 1995; 78(4):1369-1373
Web of Science PubMed


Autor/innen der Med Uni Graz:
Hinghofer-Szalkay Helmut

Dimensions Citations:

Plum Analytics:
The present study determines the effect of repeated 70 degrees head-up tilt (HUT) on plasma volume (PV) shifts by measuring blood density (BD), plasma density (PD), and hematocrit (Hct). Eight men (18-26 yr) underwent a predrink period with two supine (P1 and P3) and two HUT (P2 and P4) phases of 45 min each. At the end of P4 they drank 10 ml/kg body wt of isotonic (290 mosmol/kg) sodium chloride (Iso) or hypotonic (< 10 mosmol/kg) unsweetened tea (Hypo) or nothing [control (Con)]. The following periods continued the supine (P5, P7)/upright (P6) sequence. BD and PD were measured from ear lobe blood; they were different (P < 0.05) between Con, Hypo, and Iso P6 and P7. The density of fluid that moved between intra- and extravascular compartments was 1,008.2 +/- 0.4 g/l and did not differ with test situations. In Con (P3, P5, P7), supine PV steadily decreased compared with P1 (P < 0.05). PV in P1, P2, and P3 of all treatments averaged 120 +/- 1, 101 +/- 1, and 115 +/- 1%, respectively, of PV in P4. Tilt-induced PV shifts ranged from -9.7 to -16.7% compared with PV during the respective previous phases. After drinking, PV increased (P < 0.05) above Con values at the end of P7 by 12.9% with Iso and by 6.6% with Hypo. Progressive hemoconcentration occurred in the nondrink supine periods; isotonic saline ingestion increased supine PV to Con level but did not stop or reverse the decrease of upright hemoconcentration.(ABSTRACT TRUNCATED AT 250 WORDS)
Find related publications in this database (using NLM MeSH Indexing)
Adolescent -
Adult -
Data Interpretation, Statistical -
Drinking -
Extracellular Space - physiology
Fluid Shifts - physiology
Hematocrit - physiology
Humans - physiology
Male - physiology
Microcirculation - physiology
Plasma Volume - physiology
Posture - physiology

Find related publications in this database (Keywords)
Fluid Shifts
Interstitial Tissue
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