Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Rössler, A; László, Z; Kvas, E; Hinghofer-Szalkay, HG.
Plasma hyaluronan concentration: no circadian rhythm but large effect of food intake in humans.
Eur J Appl Physiol Occup Physiol. 1998; 78(6):573-577
Doi: 10.1007%2Fs004210050463
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- Führende Autor*innen der Med Uni Graz
- Rössler Andreas
- Co-Autor*innen der Med Uni Graz
- Hinghofer-Szalkay Helmut
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- Abstract:
- This study was designed to determine if a circadian rhythm in plasma hyaluronan concentration [HA] exists in the absence of physical activity, and if plasma [HA] is associated with feeding in human subjects. Five persons were studied under standardized conditions, blood samples being taken between 0600 and 2200 hours at 30-min intervals. Any orthostatic challenge and muscle activity was abolished by immobilization by a 6 degrees head-down bed-rest, and the effect of a quasi-continuous ingestion of energy compared a normal, three-portion diet of equivalent energy content or to fasting. Reproducibility of HA profiles on two consecutive half-days was also studied. A highly sensitive immunoassay was used to determine plasma [HA]. The data indicated that without physical activity and without food ingestion, [HA] was unchanged and displayed no diurnal rhythm. In addition, we observed that [HA] increased after the first food intake, peaking after 60 min, and concluded from our results that without ingestion of a larger meal, and sessions of postural or muscle activity, no circadian plasma [HA] rhythm exists.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Bed Rest -
- Blood Pressure - physiology
- Circadian Rhythm - physiology
- Eating - physiology
- Heart Rate - physiology
- Humans - physiology
- Hyaluronic Acid - blood
- Lymph - physiology
- Male - physiology
- Posture - physiology
- Find related publications in this database (Keywords)
- Bedrest
- Circadian Rhythm
- Hyaluronan
- Hyaluronic Acid
- Lymph Flux