Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Burja, B; Kuret, T; Sodin-Semrl, S; Lakota, K; Rotar, Ž; Ješe, R; Mrak-Poljšak, K; Žigon, P; Thallinger, GG; Feichtinger, J; Čučnik, S; Tomšič, M; Praprotnik, S; Hočevar, A.
A concise review of significantly modified serological biomarkers in giant cell arteritis, as detected by different methods.
Autoimmun Rev. 2018; 17(2):188-194
Doi: 10.1016/j.autrev.2017.11.022
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Feichtinger Julia
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- Abstract:
- Giant cell arteritis (GCA) is a primary systemic vasculitis present in subjects older than 50years with involvement of large- and medium-sized arteries. Early diagnosis for GCA is essential to prevent serious complications, such as permanent vision loss and/or cerebrovascular events. Elevated inflammatory cytokines, with acute phase and other proteins dominate large- and medium-sized arteries leading to stenosis or occlusion of arterial lumen. To date, there are no reliable serological markers for monitoring GCA. The review aims to provide concise overview of published GCA studies in order to: a) identify significantly changed serological biomarkers in GCA and compare the influences of techniques for marker evaluation and b) investigate most promising markers in GCA using analyte frequency and meta-analysis. Copyright © 2017 Elsevier B.V. All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Biomarkers - blood
- Enzyme-Linked Immunosorbent Assay - methods
- Giant Cell Arteritis - diagnosis
- Humans -
- Find related publications in this database (Keywords)
- Giant cell arteritis
- Biomarkers
- Serology
- ELISA
- Luminex multiarray