Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

Logo MUG-Forschungsportal

Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid Stoffw Microb

Bugger, H; Abel, ED.
Mitochondria in the diabetic heart.
Cardiovasc Res. 2010; 88(2): 229-240. Doi: 10.1093/cvr/cvq239 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG


Führende Autor*innen der Med Uni Graz
Bugger Heiko Matthias

Dimensions Citations:

Plum Analytics:

Scite (citation analytics):

Diabetes mellitus increases the risk of developing cardiovascular diseases such as coronary artery disease and heart failure. Studies have shown that the heart failure risk is increased in diabetic patients even after adjusting for coronary artery disease and hypertension. Although the cause of this increased heart failure risk is multifactorial, increasing evidence suggests that derangements in cardiac energy metabolism play an important role. In particular, abnormalities in cardiomyocyte mitochondrial energetics appear to contribute substantially to the development of cardiac dysfunction in diabetes. This review will summarize these abnormalities in mitochondrial function and discuss potential underlying mechanisms.
Find related publications in this database (using NLM MeSH Indexing)
Animals -
Calcium - metabolism
Diabetes Complications - etiology
Diabetes Complications - metabolism
Diabetes Complications - pathology
Energy Metabolism -
Heart Diseases - etiology
Heart Diseases - metabolism
Heart Diseases - pathology
Humans -
Insulin - metabolism
Mitochondria, Heart - metabolism
Mitochondria, Heart - pathology
Mitochondrial Proteins - metabolism
Myocardium - metabolism
Myocardium - pathology
Oxidative Stress -
Protein Processing, Post-Translational -
Risk Factors -
Signal Transduction -

Find related publications in this database (Keywords)
© Med Uni Graz Impressum