Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

Logo MUG-Forschungsportal

Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid Stoffw Microb

Zweiker, D; Zweiker, R; Winkler, E; Roesch, K; Schumacher, M; Stepan, V; Krippl, P; Bauer, N; Heine, M; Reicht, G; Zweiker, G; Sprenger, M; Watzinger, N.
Association between subjective risk perception and objective risk estimation in patients with atrial fibrillation: a cross-sectional study.
BMJ Open. 2017; 7(9):e018242-e018242 Doi: 10.1136/bmjopen-2017-018242 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG


Führende Autor*innen der Med Uni Graz
Zweiker David
Co-Autor*innen der Med Uni Graz
Schumacher Martin
Sprenger Martin
Stepan Vinzenz
Watzinger Norbert
Zweiker Robert

Dimensions Citations:

Plum Analytics:

Scite (citation analytics):

Oral anticoagulation (OAC) is state-of-the-art therapy for atrial fibrillation (AF), the most common arrhythmia worldwide. However, little is known about the perception of patients with AF and how it correlates with risk scores used by their physicians. Therefore, we correlated patients' estimates of their own stroke and bleeding risk with the objectively predicted individual risk using CHA2DS2-VASc and HAS-BLED scores. Cross-sectional prevalence study using convenience sampling and telephone follow-up. Eight hospital departments and one general practitioner in Austria. Patients' perception of stroke and bleeding risk was opposed to commonly used risk scoring. Patients with newly diagnosed AF and indication for anticoagulation. Comparison of subjective risk perception with CHA2DS2-VASc and HAS-BLED scores showing possible discrepancies between subjective and objective risk estimation. Patients' judgement of their own knowledge on AF and education were also correlated with accuracy of subjective risk appraisal. Ninety-one patients (age 73±11 years, 45% female) were included in this study. Subjective stroke and bleeding risk estimation did not correlate with risk scores (ρ=0.08 and ρ=0.17). The majority of patients (57%) underestimated the individual stroke risk. Patients feared stroke more than bleeding (67% vs 10%). There was no relationship between accurate perception of stroke and bleeding risks and education level. However, we found a correlation between the patients' judgement of their own knowledge of AF and correct assessment of individual stroke risk (ρ=0.24, p=0.02). During follow-up, patients experienced the following events: death (n=5), stroke (n=2), bleeding (n=1). OAC discontinuation rate despite indication was 3%. In this cross-sectional analysis of OAC-naive patients with AF, we found major differences between patients' perceptions and physicians' assessments of risks and benefits of OAC. To ensure shared decision-making and informed consent, more attention should be given to evidence-based and useful communication strategies. NCT03061123. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
Find related publications in this database (using NLM MeSH Indexing)
Aged -
Aged, 80 and over -
Anticoagulants - therapeutic use
Atrial Fibrillation - complications
Atrial Fibrillation - drug therapy
Atrial Fibrillation - psychology
Cross-Sectional Studies -
Educational Status -
Female -
Health Knowledge, Attitudes, Practice -
Hemorrhage - chemically induced
Humans -
Judgment -
Male -
Middle Aged -
Perception -
Risk Assessment -
Stroke - etiology
Surveys and Questionnaires -

© Med Uni Graz Impressum