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Gottschalk, I; Strizek, B; Mallmann, MR; Müller, A; Geipel, A; Gembruch, U; Klaritsch, P; Csapo, B; Berg, C.
Outcome of Bronchopulmonary Sequestration with Massive Pleural Effusion after Intrafetal Vascular Laser Ablation.
Fetal Diagn Ther. 2018; 44(2):149-155
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Autor/innen der Med Uni Graz:
Csapo Bence
Klaritsch Philipp

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Plum Analytics:
To assess the outcome of 12 fetuses with bronchopulmonary sequestration (BPS) and massive pleural effusion after intrafetal vascular laser ablation (VLA). All fetuses with BPS and massive pleural effusion that were treated with intrafetal VLA during a 5-year period (2012-2016) were reviewed for safety, intrauterine course, and postnatal outcome. In the study period, 12 fetuses with BPS were treated with VLA. In 7 (58.3%) fetuses, complete cessation of blood flow was achieved after the first VLA, while in 5 (41.7%) fetuses, residual perfusion of the feeding vessel was demonstrated at follow-up. A second intervention was successful in 4 of 5 (80%) fetuses. Overall, in 11 of 12 (91.7%) fetuses, complete coagulation of the feeding vessel could be achieved, followed by a reduction in size or complete resolution of the BPS. All 11 fetuses with successful prenatal intervention were live-born at a median gestational age of 39+1 (range, 37+5-41+2) weeks. Postnatally, 2 (18.2%) of the 11 newborns underwent sequestrectomy, as well as the preterm newborn on which a second fetal intervention was not feasible. VLA is an effective and safe treatment of BPS that appears to be of benefit in improving prognosis and decreasing the need for postnatal sequestrectomy. © 2017 S. Karger AG, Basel.
Find related publications in this database (using NLM MeSH Indexing)
Bronchopulmonary Sequestration - diagnostic imaging
Bronchopulmonary Sequestration - therapy
Cohort Studies -
Female -
Fetal Therapies - methods
Humans -
Laser Therapy - methods
Pleural Effusion - diagnostic imaging
Pleural Effusion - therapy
Pregnancy -
Retrospective Studies -
Treatment Outcome -
Ultrasonography, Prenatal - methods

Find related publications in this database (Keywords)
Bronchopulmonary sequestration
Intrauterine intervention
Prenatal diagnosis
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