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Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid

Wolny, R; Pregowski, J; Kruk, M; Kepka, C; Mintz, GS; Toth, GG; Debski, A; Ciszewski, M; Kukula, K; Opolski, MP; Chmielak, Z; Witkowski, A.
Computed tomography angiography versus angiography for guiding percutaneous coronary interventions in bifurcation lesions - A prospective randomized pilot study.
J Cardiovasc Comput Tomogr. 2017; 11(2):119-128
Web of Science PubMed FullText FullText_MUG

 

Autor/innen der Med Uni Graz:
Toth-Gayor Gabor
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Abstract:
There is no data on the impact of coronary computed tomography angiography (coronary CTA), as an addition to angiography, on the outcomes of percutaneous coronary interventions (PCI) in bifurcation lesions. Patients with stable coronary artery disease scheduled for elective bifurcation PCI were randomized 1:1 to planning the procedure based on coronary CTA and angiography (CTA group) or angiography alone (CA group). The primary efficacy endpoint was the immediate angiographic result. Secondary efficacy endpoints were: a) procedural characteristics and b) postprocedural fractional flow reserve (FFR) in the side branch (SB) in a subgroup of patients. Safety outcomes were: a) periprocedural myocardial infarction, b) contrast use and c) radiation dose. PCI of 45 lesions in the CTA group and 47 lesions in the CA group was performed. Postprocedural lumen diameters in the main branch (MB) and SB, frequency of SB compromise or occlusion and mean SB FFR values were not different between study groups. Two or more stents were implanted less frequently in the CTA group than in the CA group (18% vs. 43%, p = 0.01). This difference was driven by less frequent MB 2-stent overlap in the CTA group (7 vs. 21%, p = 0.046) and numerically less SB stenting (11% vs. 21%, p = 0.07). Proximal optimization technique was used more frequently in the CTA group (44% vs. 21%, p = 0.018). CTA-assisted bifurcation PCI leads to similar immediate results compared with angiography alone, however is associated with higher use of single-stent procedures with proximal optimization, less frequent 2-stent overlap and less SB stenting. Copyright © 2017 Society of Cardiovascular Computed Tomography. All rights reserved.
Find related publications in this database (using NLM MeSH Indexing)
Aged -
Computed Tomography Angiography -
Coronary Angiography - methods
Coronary Artery Disease - diagnostic imaging
Coronary Artery Disease - physiopathology
Coronary Artery Disease - therapy
Coronary Vessels - diagnostic imaging
Coronary Vessels - physiopathology
Female -
Fractional Flow Reserve, Myocardial -
Humans -
Male -
Middle Aged -
Myocardial Infarction - etiology
Percutaneous Coronary Intervention - adverse effects
Percutaneous Coronary Intervention - instrumentation
Pilot Projects -
Poland -
Predictive Value of Tests -
Prospective Studies -
Radiation Dosage -
Radiation Exposure -
Single-Blind Method -
Stents -
Treatment Outcome -

Find related publications in this database (Keywords)
Coronary CIA
Percutaneous coronary intervention
Bifurcations
Planning
Side branch
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