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SHR Neuro Krebs Kardio Lipid

Veltman, ES; Moojen, DJ; Glehr, M; Poolman, RW.
Similar rate of infection eradication for functional articulating, prefabricated and custom-made spacers in 2-stage revision of the infected total hip: a literature review.
Hip Int. 2016; 26(4):319-326
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Autor/innen der Med Uni Graz:
Glehr Mathias

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2-stage revision with the use of an antibiotic-loaded interval spacer is therapy of choice in late periprosthetic joint infection for most surgeons. For the spacer, either a prefabricated, functional articulating or custom-made spacer can be used. Little is known about which type of spacer provides optimal outcome after 2-stage revision. The aim of this study was to determine which type of spacer provides the best results, when used in 2-stage revision of an infected THA. We performed a systematic review of the literature to analyse which type of interval spacer provides highest infection eradication rate and best functional outcome after a minimum 2 year follow-up. Exclusion criteria were follow-up of less than 2 years, single-stage revision, or 2-stage revision without use of a spacer. 25 studies were included. Infection eradication rate was similar with rates of 96%, 93% and 95% for the prefabricated-, functional articulating- and custom-made spacers respectively. Functional outcome was scarcely described. Postoperative HHS was 81, 90 and 83 respectively. Functional articulating spacers achieve a comparable rate of infection eradication in the treatment of periprosthetic hip joint infections as compared to preformed or custom-made antibiotic-loaded spacers. There is insufficient evidence concerning rehabilitation and functional outcome after 2-stage revision hip arthroplasty to advocate or discourage the use of either kind of interval spacer.
Find related publications in this database (using NLM MeSH Indexing)
Anti-Bacterial Agents - administration & dosage
Arthroplasty, Replacement, Hip -
Hip Prosthesis -
Humans -
Prosthesis Design -
Prosthesis-Related Infections - therapy
Recovery of Function -
Reoperation -
Treatment Outcome -

Find related publications in this database (Keywords)
Antibiotic-loaded spacer
Functional articulating spacer
Periprosthetic joint infection
Total hip arthroplasty
2-stage revision
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