Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid

Ramlau, R; Cufer, T; Berzinec, P; Dziadziuszko, R; Olszewski, W; Popper, H; Bajcic, P; Dusšk, L; Zbozinkova, Z; Pirker, R; INSIGHT study team.
Epidermal Growth Factor Receptor Mutation-Positive Non-Small-Cell Lung Cancer in the Real-World Setting in Central Europe: The INSIGHT Study.
J Thorac Oncol. 2015; 10(9):1370-1374 [OPEN ACCESS]
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Autor/innen der Med Uni Graz:
Popper Helmuth
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Abstract:
The ImplementatioN of perSonalized medicine In NSCLC in Central Europe: EGFR testing, Histopathology, and clinical feaTures (INSIGHT) observational study assessed both implementation of epidermal growth factor receptor (EGFR) mutation testing and treatment of patients with advanced EGFR mutation-positive non-small-cell lung cancer (NSCLC) in a real-world setting in Central Europe. A total of 1785 patients from 14 cancer centers of six Central European countries were enrolled. EGFR mutations were detected in tumors of 13.8% of the patients. More than 70% of patients with advanced EGFR mutation-positive NSCLC received EGFR tyrosine kinase inhibitors as first-line therapy. The INSIGHT study demonstrated the establishment of EGFR mutation testing, a mutation rate consistent with other Caucasian patients populations, and adherence to current guidelines regarding treatment of patients with EGFR mutation-positive tumors in Central Europe.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Aged -
Aged, 80 and over -
Carcinoma, Non-Small-Cell Lung - genetics
Carcinoma, Non-Small-Cell Lung - pathology
ErbB Receptors - genetics
ErbB Receptors - metabolism
Europe -
Humans -
Lung Neoplasms - genetics
Lung Neoplasms - pathology
Middle Aged -
Mutation -
Young Adult -

Find related publications in this database (Keywords)
Targeted therapy
INSIGHT
EGFR mutations
Molecular analysis
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