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Metnitz, B; Schaden, E; Moreno, R; Le Gall, JR; Bauer, P; Metnitz, PG; ASDI Study Group.
Austrian validation and customization of the SAPS 3 Admission Score.
Intensive Care Med. 2009; 35(4):616-622
Doi: 10.1007/s00134-008-1286-2
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- Führende Autor*innen der Med Uni Graz
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Metnitz Philipp
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- Abstract:
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To test the prognostic performance of the SAPS 3 Admission Score in a regional cohort and to empirically test the need and feasibility of regional customization.
Prospective multicenter cohort study.
Data on a total of 2,060 patients consecutively admitted to 22 intensive care units in Austria from October 2, 2006 to February 28, 2007.
The database includes basic variables, SAPS 3, length-of-stay and outcome data. The original SAPS 3 Admission Score overestimated hospital mortality in Austrian intensive care patients through all strata of the severity-of-illness. This was true for both available equations, the General and the Central and Western Europe equation. For this reason a customized country-specific model was developed, using cross-validation techniques. This model showed excellent calibration and discrimination in the whole cohort (Hosmer-Lemeshow goodness-of-fit: H = 4.50, P = 0.922; C = 5.61, P = 0.847, aROC, 0.82) as well as in the various tested subgroups.
The SAPS 3 Admission Score's general equation can be seen as a framework for addressing the problem of outcome prediction in the general population of adult ICU patients. For benchmarking purposes, region-specific or country-specific equations seem to be necessary in order to compare ICUs on a similar level.
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Aged -
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Aged -
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Critical Care - standards
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Critical Care - statistics & numerical data
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Data Collection - standards
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Demography -
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Female -
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Hospital Mortality - trends
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Humans -
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Intensive Care Units - statistics & numerical data
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Length of Stay - statistics & numerical data
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Male -
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Patient Admission -
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Predictive Value of Tests -
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Prognosis -
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Quality Assurance, Health Care - standards
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Reproducibility of Results -
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Severity-of-illness
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Outcome
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Prognosis
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Customization
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SAPS 3