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SHR Neuro Krebs Kardio Lipid Stoffw Microb

Gattringer, T; Ferrari, J; Knoflach, M; Seyfang, L; Horner, S; Niederkorn, K; Culea, V; Beitzke, M; Lang, W; Enzinger, C; Fazekas, F.
Sex-related differences of acute stroke unit care: results from the Austrian stroke unit registry.
Stroke. 2014; 45(6):1632-1638 Doi: 10.1161/STROKEAHA.114.004897 [OPEN ACCESS]
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Führende Autor*innen der Med Uni Graz
Fazekas Franz
Gattringer Thomas
Co-Autor*innen der Med Uni Graz
Beitzke Markus
Enzinger Christian
Gold Valeriu
Horner Susanna
Niederkorn Kurt

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Sex-related differences in quality of acute stroke care are an important concern with limited data available, specifically regarding stroke unit (SU) setting. We used the prospective nationwide Austrian SU registry to address this issue. Our analysis covered an 8-year time period (January 2005 to December 2012) during which all patients with transient ischemic attack or ischemic stroke admitted to 1 of 35 Austrian SU had been captured in the registry. These data were analyzed for age-adjusted preclinical and clinical characteristics and quality of acute stroke care in men and women. In addition, we assessed the outcome at 3 months in multivariate analysis. A total of 47 209 individuals (47% women) had received SU care. Women were significantly older (median age: 77.9 versus 70.3 years), had higher pre-existing disability and more severe strokes. Correcting for age, no significant sex-related differences in quality of care were identified with comparable onset-to-door times, times to and rates of neuroimaging, as well as door-to-needle times and rates of intravenous thrombolysis (14.5% for both sexes). Despite equal acute stroke care and a comparable rate of neurorehabilitation, women had a worse functional outcome at 3-month follow-up (modified Rankin scale 3-5: odds ratio, 1.26; 95% confidence interval [1.17-1.36]), but a lower mortality (odds ratio, 0.70; 95% confidence interval [0.78-0.88]) after correcting for confounders. We identified no disproportions in quality of care in the acute SU setting between men and women, but the outcome was significantly different. Further studies on the poststroke period including socioeconomic aspects are needed to clarify this finding. © 2014 American Heart Association, Inc.
Find related publications in this database (using NLM MeSH Indexing)
Aged -
Aged, 80 and over -
Aged, 80 and over - epidemiology
Brain Ischemia - mortality Brain Ischemia - physiopathology Brain Ischemia - therapy
Female -
Follow-Up Studies -
Humans -
Male -
Middle Aged -
Registries -
Retrospective Studies -
Sex Characteristics -
Stroke - mortality Stroke - physiopathology Stroke - therapy

Find related publications in this database (Keywords)
ischemic attack, transient
ischemic stroke
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