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SHR Neuro Krebs Kardio Lipid

Aigner, B; Ugurel, S; Kaddu, S; Becker, JC.
[Cutaneous sarcomas: update on selected fibrohistiocytic and myofibroblastic tumors].
Hautarzt. 2014; 65(7):614-622
Web of Science PubMed FullText FullText_MUG

 

Autor/innen der Med Uni Graz:
Becker Jürgen Christian
Kaddu Steven
Sadoghi Birgit
Ugurel-Becker Selma
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Abstract:
Malignant fibrohistiocytic tumors are a heterogeneous group of mesenchymal neoplasms that may occur in the skin and subcutaneous tissues. Diagnosis of these tumors may be difficult, as they are rare, and a wide morphological diversity of types and subtypes has been described. In this update, relevant aspects of selected entities like dermatofibrosarcoma protuberans, desmoid tumor, atypical fibroxanthoma, pleomorphic dermal sarcoma, and myxofibrosarcoma are discussed according to the WHO classification of 2013. The typical clinical feature of these tumors is their mostly asymptomatic appearance. For diagnosis, the histologic workup is therefore the key feature; herein immunohistochemistry as well as molecular diagnostics become increasingly important. The primary treatment for locally resectable tumors is complete surgical removal; chemotherapy, radiation, and targeted therapies with kinase inhibitors are available for inoperable and metastatic disease.
Find related publications in this database (using NLM MeSH Indexing)
Chemoradiotherapy - methods
Dermatologic Surgical Procedures - methods
Humans -
Molecular Targeted Therapy - methods
Protein Kinase Inhibitors - therapeutic use
Sarcoma - diagnosis
Sarcoma - therapy
Skin Neoplasms - diagnosis
Skin Neoplasms - therapy

Find related publications in this database (Keywords)
Histology
Diagnosis
Dermatofibrosarcoma protuberans
Desmoid tumor
Therapy
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