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SHR Neuro Krebs Kardio Lipid

Faschinger, C; Mossbock, G; Strohmaier, C; Reitsamer, HA.
24-hour "intraocular pressure" measurement with sensory contact lens Triggerfish: from euphoria to disillusion
SPEKTRUM AUGENHEILKD. 2011; 25(4): 262-268.
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Autor/innen der Med Uni Graz:
Faschinger Christoph
Mossböck Georg

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BACKGROUND: The first trials with the sensory contact lens Triggerfish checking the safety and tolerability in human eyes were satisfactory. This specific contact lens measures the changes of the peripheral corneal curvature due to changes of the intraocular pressure within 24 hours continuously and wirelessly. The aims of our study were (1) to perform these measurements in enucleated human eyes with stepwise change of the intraocular pressure and (2) in a healthy human eye when changing the body positions. MATERIAL AND METHODS: (1) After canulation of the enucleated human eye and after the placement of the Triggerfish contact lens the intraocular pressure was increased stepwise and monitored as well as the data from the contact lens. (2) After a period of adaption of the Triggerfish contact lens in a vertical body position the body was brought in a supine and head-down position. At any time of change of the position the intraocular pressure of the second eye was checked by a handhold applanation tonometer. RESULTS: (1) The Triggerfish did not reveal correlating results to the stepwise increase of the intraocular pressure in an enucleated human eye. (2) The Triggerfish did not reveal corresponding results to the intraocular pressure values measured by applanation tonometer of the second eye after changing body positions, even not when the experiment was repeated. CONCLUSIONS: Despite perfect laboratory conditions reproducible measurements of changes of the corneal curvature induced by changes of the intraocular pressure could not be obtained. Changes of body/head positions would expect to produce changes in the intraocular pressure and therefore changes in the profile of the Triggerfish, but these anticipated changes did not correspond to the values gained by applanation tonometry. The reasons why are yet to be examined to judge the Triggerfish reliably.

Find related publications in this database (Keywords)
Sensory contact lens
intraocular pressure
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