Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Neuwirt, E; Gorka, O; Saller, BS; Groß, CJ; Madl, T; Groß, O.
NLRP3 as a sensor of metabolism gone awry.
CURR OPIN BIOTECH. 2021; 68: 300-309.
Doi: 10.1016/j.copbio.2021.03.009
Web of Science
PubMed
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FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Madl Tobias
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- Abstract:
- The NLRP3 inflammasome is an important player in innate immunity and pathogenic inflammation. Numerous studies have implicated it in sensing endogenous danger signals, yet the precise mechanisms remain unknown. Here, we review the current knowledge on the organismal and cellular metabolic triggers engaging NLRP3, and the mechanisms involved in integrating the diverse signals.
- Find related publications in this database (using NLM MeSH Indexing)
- Humans - administration & dosage
- Immunity, Innate - administration & dosage
- Inflammasomes - administration & dosage
- Inflammation - administration & dosage
- NLR Family, Pyrin Domain-Containing 3 Protein - genetics