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SHR Neuro Krebs Kardio Lipid Stoffw Microb

Neuwirt, E; Gorka, O; Saller, BS; Groß, CJ; Madl, T; Groß, O.
NLRP3 as a sensor of metabolism gone awry.
CURR OPIN BIOTECH. 2021; 68: 300-309. Doi: 10.1016/j.copbio.2021.03.009
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Co-Autor*innen der Med Uni Graz
Madl Tobias

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The NLRP3 inflammasome is an important player in innate immunity and pathogenic inflammation. Numerous studies have implicated it in sensing endogenous danger signals, yet the precise mechanisms remain unknown. Here, we review the current knowledge on the organismal and cellular metabolic triggers engaging NLRP3, and the mechanisms involved in integrating the diverse signals.
Find related publications in this database (using NLM MeSH Indexing)
Humans - administration & dosage
Immunity, Innate - administration & dosage
Inflammasomes - administration & dosage
Inflammation - administration & dosage
NLR Family, Pyrin Domain-Containing 3 Protein - genetics

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