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SHR Neuro Krebs Kardio Lipid Stoffw Microb

Holzer, P; Hassan, AM; Jain, P; Reichmann, F; Farzi, A.
Neuroimmune pharmacological approaches.
Curr Opin Pharmacol. 2015; 25:13-22 Doi: 10.1016/j.coph.2015.09.003 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG


Führende Autor*innen der Med Uni Graz
Holzer Peter
Co-Autor*innen der Med Uni Graz
Farzi Aitak
JAIN Piyush
Reichmann Florian

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Intestinal inflammation is a major health problem which impairs the quality of life, impacts mental health and is exacerbated by stress and psychiatric disturbances which, in turn, can affect disease prognosis and response to treatment. Accumulating evidence indicates that the immune system is an important interface between intestinal inflammation and the enteric, sensory, central and autonomic nervous systems. In addition, the neuroimmune interactions originating from the gastrointestinal tract are orchestrated by the gut microbiota. This article reviews some major insights into this complex homeostatic network that have been achieved during the past two years and attempts to put these advances into perspective with novel opportunities of pharmacological intervention. Copyright © 2015 Elsevier Ltd. All rights reserved.
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