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SHR Neuro Krebs Kardio Lipid

Sunitsch, S; Gilg, M; Kashofer, K; Leithner, A; Liegl-Atzwanger, B; Beham-Schmid, C.
Case Report: Epstein-Barr-Virus negative diffuse large B-cell lymphoma detected in a peri-prosthetic membrane.
Diagn Pathol. 2016; 11(1):80-80 (- Case Report) [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Autor/innen der Med Uni Graz:
Beham-Schmid Christine
Gilg Magdalena Maria
Kashofer Karl
Leithner Andreas
Liegl-Atzwanger Bernadette
Sunitsch Sandra
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Abstract:
Primary bone lymphomas (PBL) are extremely rare malignant neoplasms. The most commonly described subtype of PBL is diffuse large B-cell lymphoma (DLBCL). DLBCL within peri-prosthetic membrane of a joint is exceedingly rare. To the best of our knowledge this case is the second reported Epstein-Bar-Virus (EBV) negative DLBCL in a peri-prosthetic membrane in the literature. We report an 80 year old female patient who developed a DLBCL with chronic inflammation in association to a metallic implant in the left knee. This lymphoma in contrast to the usually described DLBCL in the peri-prosthetic membrane was EBV negative by EBER in situ hybridization as well as by polymerase chain reaction (PCR). This report challenges the concept of DLBCL associated with chronic inflammation and raises the question of other pathogenetic factors involved in the pathogenesis of this rare disease.
Find related publications in this database (using NLM MeSH Indexing)
Aged, 80 and over -
Arthroplasty, Replacement, Knee - adverse effects
Arthroplasty, Replacement, Knee - instrumentation
Biomarkers, Tumor - analysis
Biopsy -
Chemoradiotherapy -
Female -
Humans -
Immunohistochemistry -
Knee Prosthesis -
Lymphoma, Large B-Cell, Diffuse - chemistry
Lymphoma, Large B-Cell, Diffuse - etiology
Lymphoma, Large B-Cell, Diffuse - pathology
Lymphoma, Large B-Cell, Diffuse - therapy
Metals -
Prosthesis Design -
Prosthesis Failure -
Risk Factors -
Treatment Outcome -

Find related publications in this database (Keywords)
Primary bone lymphoma
Diffuse large B-cell lymphoma
Epstein-Barr-Virus negative
Knee arthroplasty
Periprosthetic membrane
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