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Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid

Kühn, KD; Höntzsch, D.
Augmentation with PMMA cement].
Unfallchirurg. 2015; 118(9):737-748
Web of Science PubMed FullText FullText_MUG


Autor/innen der Med Uni Graz:
Kühn Klaus-Dieter

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Plum Analytics:
Cements based on polymethyl methacrylate (PMMA) can be used without any problem in a variety of clinical augmentations. Cement-related complications in surgical procedures involving PMMA cements, such as embolism, thermal necrosis, toxicity and hypersensitivity, are often due to other causes. Knowledge about the properties of the cement helps the user to safely employ PMMA cements in augmentations. High radio-opacity is required in vertebral body augmentations and this is provided in particular by zirconium dioxide. In vertebral body augmentations, a low benzoyl peroxide (BPO) content can considerably prolong the liquid dough phase. In augmentations with cement fillings in the region of a tumor, a high BPO content can specifically increase the peak temperature of the PMMA cement. In osteosynthetic augmentations with PMMA, necrosis is rare because heat development in the presence of metallic implants is low due to heat conduction via the implant. Larger cement fillings where there is no heat conduction via metal implants can exhibit substantially higher peak temperatures. The flow properties of PMMA cements are of particular importance for the user to allow optimum handling of PMMA cements. In patients with hypersensitivity to antibiotics, there is no need to avoid the use of PMMA as there are sufficient PMMA-based alternatives. The PMMA cements are local drug delivery systems and antibiotics, antiseptics, antimycotics and also cytostatics can be mixed with the cement. Attention must be paid to antagonistic and synergistic effects.
Find related publications in this database (using NLM MeSH Indexing)
Bone Cements - adverse effects
Bone Cements - chemistry
Bone Cements - therapeutic use
Cementoplasty - methods
Combined Modality Therapy - methods
Evidence-Based Medicine -
Fracture Fixation, Internal - instrumentation
Fracture Fixation, Internal - methods
Fractures, Bone - therapy
Humans -
Polymethyl Methacrylate - adverse effects
Polymethyl Methacrylate - chemistry
Polymethyl Methacrylate - therapeutic use
Reconstructive Surgical Procedures - instrumentation
Reconstructive Surgical Procedures - methods
Treatment Outcome -

Find related publications in this database (Keywords)
Methyl methacrylate
Drug delivery systems
Polymerization heat
Polymerization shrinkage
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