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SHR Neuro Krebs Kardio Lipid

Wolf, M; Clar, H; Friesenbichler, J; Schwantzer, G; Bernhardt, G; Gruber, G; Glehr, M; Leithner, A; Sadoghi, P.
Prosthetic joint infection following total hip replacement: results of one-stage versus two-stage exchange.
Int Orthop. 2014; 38(7):1363-1368 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG


Autor/innen der Med Uni Graz:
Bernhardt Gerwin
Clar Heimo
Friesenbichler Jörg
Glehr Mathias
Gruber Gerald
Leithner Andreas
Sadoghi Patrick
Schwantzer Gerold
Wolf Matthias

Dimensions Citations:

Plum Analytics:
Prosthetic hip joint infection remains a challenging socio-economic problem. Curative treatment is usually a one- or two-stage revision surgery, but neither of these options has yet emerged as the treatment of choice. The aim of this study was to evaluate which of these methods produced superior outcomes. A retrospective study was performed including 92 patients with deep infections after implantation of primary total hip arthroplasty (THA) who had undergone either one-stage or two-stage revision surgery at a single centre. Infections were classified according to McPherson and we evaluated the rate of persisting infection or reinfection after surgical intervention. The two-stage revision surgery revealed superior outcomes for the analysed infection categories compared to the one-stage procedure except for the least serious category of infections (i.e. McPherson Stage I/A/1, early postoperative infection, no systemic comorbidities, local status uncompromised). Eradication of prosthetic infection was achieved in 94.5 % (n = 52) within the group of two-stage exchange, and 56.8 % (n = 21) of patients treated with a one-stage procedure. Outcome of patients following a one-stage or a two-stage exchange was overall significantly different with p < 0.001. Further deviations between the described two procedures were noted in the subgroups following the classification described by McPherson. Our results indicate superiority of two-stage revision surgery in case of serious infections. The authors believe that decisions on the surgical approach for the treatment of deep prosthesis infections should be made on the basis of standardized staging systems.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Aged -
Aged, 80 and over -
Arthroplasty, Replacement, Hip - adverse effects
Female -
Hip Prosthesis -
Humans -
Male -
Middle Aged -
Prosthesis-Related Infections - etiology
Prosthesis-Related Infections - surgery
Reoperation - methods
Retrospective Studies -
Young Adult -

Find related publications in this database (Keywords)
Total hip arthroplasty
Classification system
Outcome analysis
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