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SHR Neuro Krebs Kardio Lipid

Friesenbichler, J; Maurer-Ertl, W; Sadoghi, P; Lovse, T; Windhager, R; Leithner, A.
Serum metal ion levels after rotating-hinge knee arthroplasty: comparison between a standard device and a megaprosthesis.
Int Orthop. 2012; 36(3):539-544 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG


Autor/innen der Med Uni Graz:
Friesenbichler Jörg
Leithner Andreas
Lovse Thomas
Maurer-Ertl Werner
Sadoghi Patrick
Windhager Reinhard

Dimensions Citations:

Plum Analytics:
Number of Figures: 2
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Purpose The effects of systemic metal ion exposure in patients with implants made of common prosthetic alloys continue to be a matter of concern. The aim of the study was to determine the measurement values of cobalt (Co), chromium (Cr) and molybdenum (Mo) in serum following rotating-hinge knee arthroplasty. Methods Blood was taken from 25 patients [mean follow-up 35 (range nine to 67) months] treated with megaprostheses (n=17) or standard rotating-hinge devices (n=8) and analysed using electrothermal graphite furnace atomic absorption spectrometry (ET-ASS). Results Determining the concentrations of metal ions following rotating-hinge knee arthroplasty revealed increments for Co and Cr but not Mo. Metal ion release was significantly higher in patients with megaprostheses compared to a standard rotating-hinge knee device (Co p=0,024; Cr p=0.025). Conclusion The authors believe there might be an additional metal ion release from the surface of the prosthesis and not only from the articulating surfaces because, in cases of rotating-hinge knee prosthesis, there is a metal-on-polyethylene articulation and not a direct metal-on-metal junction. Nevertheless, long-term studies are required to determine adverse effects of Co, Cr and Mo following total hip replacement and total knee arthroplasty.
Find related publications in this database (using NLM MeSH Indexing)
Adolescent -
Adult -
Aged -
Aged, 80 and over -
Arthroplasty, Replacement, Knee - adverse effects Arthroplasty, Replacement, Knee - instrumentation Arthroplasty, Replacement, Knee - methods
Chromium - blood
Cobalt - blood
Female -
Humans -
Ions -
Knee Prosthesis -
Male -
Metals - blood
Middle Aged -
Molybdenum - blood
Prosthesis Design -
Prosthesis Failure - adverse effects
Surface Properties -
Young Adult -

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