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SHR Neuro Krebs Kardio Lipid

Bauchinger, S; Lackner, H; Schwinger, W; Sovinz, P; Benesch, M; Sorantin, E; Till, H; Urban, C.
Primary renal neuroblastoma metastasizing into liver and lungs with tumor thrombus extension into the right atrium.
Klin Padiatr. 2014; 226(6-7):369-371 (- Case Report)
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Autor/innen der Med Uni Graz:
Bauchinger Sebastian
Benesch Martin
Lackner Herwig
Ritter-Sovinz Petra
Schwinger Wolfgang
Sorantin Erich
Till Holger
Urban Ernst-Christian
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Abstract:
Neuroblastomas are malignant tumors of the sympathetic nervous system. Areas of manifestation most commonly involve the abdomen, neck, thorax and pelvis. Primary renal neuroblastomas are extremely rare, only a few case reports exist worldwide, and even those are discussed controversially.We present the case of a 6-year-old girl with a renal tumor and a tumor thrombus extending into the right atrium, which radiologically appeared to be a Wilms tumor. Since the lesion did not respond to nephroblastoma-specific therapy, a biopsy from one of the liver metastases was taken, revealing the revised diagnosis of a clear cell renal cell carcinoma. Histopathology of the reference center, however, described a primary renal neuroblastoma. After adjusting the chemotherapy tumornephrectomy including the complete venous thrombus could be performed without any complications.Neuroblastoma originating from a kidney is an absolute rarity that can easily be misdiagnosed as Wilms tumor, especially, if a typical tumor thrombus with extension into the inferior vena cava is seen. Therefore neuronspecific enolase in serum as well as vanillylmandelic acid and homovanillic acid in the urine should be determined in all patients when Wilms tumor is assumed. To the best of our knowledge, this is the first published case of a primary renal neuroblastoma with a tumor thrombus extending into the right atrium. © Georg Thieme Verlag KG Stuttgart · New York.
Find related publications in this database (using NLM MeSH Indexing)
Child -
Diagnosis, Differential -
Female -
Heart Atria - pathology
Heart Neoplasms - diagnosis
Heart Neoplasms - pathology
Heart Neoplasms - secondary
Humans -
Kidney - pathology
Kidney Neoplasms - diagnosis
Kidney Neoplasms - pathology
Liver - pathology
Liver Neoplasms - diagnosis
Liver Neoplasms - pathology
Liver Neoplasms - secondary
Lung - pathology
Lung Neoplasms - diagnosis
Lung Neoplasms - pathology
Lung Neoplasms - secondary
Neoplastic Cells, Circulating - pathology
Neuroblastoma - diagnosis
Neuroblastoma - pathology
Neuroblastoma - secondary

Find related publications in this database (Keywords)
primary renal neuroblastoma
nephroblastoma
tumor thrombus
renal clear cell carcinoma
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