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Pezelj-Ribarić, S; Kqiku, L; Brumini, G; Urek, MM; Antonić, R; Kuiš, D; Glažar, I; Städtler, P.
Proinflammatory cytokine levels in saliva in patients with burning mouth syndrome before and after treatment with low-level laser therapy.
Lasers Med Sci. 2013; 28(1):297-301
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Autor/innen der Med Uni Graz:
Kqiku-Biblekaj Lumnije
Städtler Peter
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Abstract:
The aim of this study was to determine the levels of proinflammatory tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6) cytokines in whole unstimulated saliva in subjects with burning mouth syndrome (BMS) before and after treatment with low-level laser therapy (LLLT). BMS is characterized by a continuous, painful burning sensation in a clinically normal-appearing oral mucosa. A sample consisting of 40 consecutive subjects was selected on a voluntary basis from the pool of patients who presented for diagnosis and treatment of BMS at the Oral Medicine Unit of the Faculty of Medicine of the University of Rijeka. For determination of salivary levels of TNF-α and IL-6, ELISA (Sigma Immunochemicals, St. Louis, MO, USA) was performed to determine the salivary levels of TNF-α and IL-6. After 4 weeks of LLLT, the salivary levels of TNF-α and IL-6 in the experimental group decreased significantly (p < 0.001). There was no significant difference in the experimental group regarding visual analogue scale.
Find related publications in this database (using NLM MeSH Indexing)
Analysis of Variance -
Burning Mouth Syndrome - metabolism
Enzyme-Linked Immunosorbent Assay -
Female -
Humans -
Interleukin-6 - metabolism
Laser Therapy, Low-Level - methods
Male -
Middle Aged -
Pain Measurement -
Saliva - chemistry
Treatment Outcome -
Tumor Necrosis Factor-alpha - metabolism

Find related publications in this database (Keywords)
Burning mouth
Laser
Cytokine
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