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Rugani, P; Acham, S; Truschnegg, A; Obermayer-Pietsch, B; Jakse, N.
Bisphosphonate-associated osteonecrosis of the jaws: surgical treatment with ErCrYSGG-laser. Case report.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010; 110(6):e1-e6 (- Case Report)
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Autor/innen der Med Uni Graz:
Acham Stephan
Jakse Norbert
Obermayer-Pietsch Barbara
Rugani Petra
Truschnegg Astrid
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Abstract:
Bisphosphonates (BP) play an important role in concomitant therapy of certain types of cancer and multiple myeloma as well as in treatment of osteoporosis. The administration of BP has great therapeutic benefits, but correlates with a specific kind of osteonecrosis of the alveolar bone. The so-called bisphosphonate-related osteonecrosis of the jaws (BRONJ) is a rare, but often severe adverse side effect of high-dosage and long-term BP therapy. Thus far, no consensus for treatment of BRONJ has been achieved. All strategies have to take into account the insecure prognosis and danger of recurrence of clinically apparent necrosis and progression of disease. At the Department of Oral Surgery and Radiology, Medical University of Graz, an ErCrYSGG laser was successfully applied in surgical treatment of BRONJ. Stable mucosal coverage could be achieved in all of 5 cases. Laser surgery can be considered as a promising technique for the effective treatment of BRONJ. Copyright © 2010 Mosby, Inc. All rights reserved.
Find related publications in this database (using NLM MeSH Indexing)
Aged -
Aged, 80 and over -
Bone Density Conservation Agents - adverse effects
Diphosphonates - adverse effects
Disease Progression -
Female -
Follow-Up Studies -
Humans -
Imidazoles - adverse effects
Jaw Diseases - chemically induced
Jaw Diseases - surgery
Laser Therapy - methods
Lasers, Solid-State - therapeutic use
Low-Level Light Therapy -
Mandibular Diseases - chemically induced
Mandibular Diseases - surgery
Middle Aged -
Osteonecrosis - chemically induced
Osteonecrosis - surgery
Photochemotherapy -
Surgical Wound Dehiscence - etiology
Wound Healing - physiology

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