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SHR Neuro Krebs Kardio Lipid

Yu, ZZ; Wolf, P.
How It Works The Immunology Underlying Phototherapy
DERMATOL CLIN. 2020; 38(1): 37-53.
Web of Science PubMed FullText FullText_MUG

 

Autor/innen der Med Uni Graz:
Wolf Peter
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Abstract:
Phototherapeutic modalities induce apoptosis of keratinocytes and immune cells, impact cytokine production, downregulate the IL-23/Th17 axis, and induce regulatory T cells. As in anti-IL-17 or anti-IL-23 antibody treatment, the dual action of phototherapy on skin and the immune system is likely responsible for sustained resolution of lesions in diseases such as psoriasis. In cutaneous T cell lymphoma, phototherapy may function by causing tumor cell apoptosis and eliminating the neoplastic and inflammatory infiltrate. Further research on phototherapeutic mechanisms will help advance, optimize, and refine dermatologic treatments and may open up novel avenues for treatment strategies in dermatology and beyond.

Find related publications in this database (Keywords)
Phototherapy
UV radiation
Apoptosis
Immunosuppression
Urocanic acid
Platelet-activating factor
IL-23TTH17 axis
Regulatory T cells (Tregs center dot)
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