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Walsh, NM; Kutzner, H; Requena, L; Cerroni, L.
Plasmacytic cutaneous pathology: A review.
J CUTAN PATHOL. 2019; 46(9): 698-708.
Web of Science PubMed FullText FullText_MUG

 

Autor/innen der Med Uni Graz:
Cerroni Lorenzo
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Abstract:
We review the spectrum of cutaneous disorders associated with inflammatory and neoplastic plasmacytic pathology. Because plasma cells are derived from B-lymphocytes our overview includes discussion of certain lymphoplasmacytic proliferations. It is structured along histopathological lines, addressing conditions characterized by (a) cutaneous plasma cell infiltrates, (b) deposits of plasma cell products or their derivatives in the skin and (c) miscellaneous, poorly understood cutaneous complications of plasmacytic disorders. Lesions arising primarily in the skin and those due to cutaneous involvement by multisystem disorders are addressed. The range includes a spectrum of tumefactive and circulatory manifestations. We highlight key clinical and pathological features of the different conditions and outline recent advances in our understanding of these entities. By emphasizing the dermatopathological characteristics of this spectrum of disorders we hope to hone the diagnostic accuracy of practitioners in the field. © 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

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