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SHR Neuro Krebs Kardio Lipid

Dirschka, T; Gupta, G; Micali, G; Stockfleth, E; Basset-Séguin, N; Del Marmol, V; Dummer, R; Jemec, GBE; Malvehy, J; Peris, K; Puig, S; Stratigos, AJ; Zalaudek, I; Pellacani, G.
Real-world approach to actinic keratosis management: practical treatment algorithm for office-based dermatology.
J Dermatolog Treat. 2017; 28(5):431-442 [OPEN ACCESS]
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Autor/innen der Med Uni Graz:
Zalaudek Iris
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Abstract:
Actinic keratosis (AK) is a chronic skin disease in which multiple clinical and subclinical lesions co-exist across large areas of sun-exposed skin, resulting in field cancerisation. Lesions require treatment because of their potential to transform into invasive squamous cell carcinoma. This article aims to provide office-based dermatologists and general practitioners with simple guidance on AK treatment in daily clinical practice to supplement existing evidence-based guidelines. Novel aspects of the proposed treatment algorithm include differentiating patients according to whether they have isolated scattered lesions, lesions clustered in small areas or large affected fields without reference to specific absolute numbers of lesions. Recognising that complete lesion clearance is rarely achieved in real-life practice and that AK is a chronic disease, the suggested treatment goals are to reduce the number of lesions, to achieve long-term disease control and to prevent disease progression to invasive squamous cell carcinoma. In the clinical setting, physicians should select AK treatments based on local availability, and the presentation and needs of their patients. The proposed AK treatment algorithm is easy-to-use and has high practical relevance for real-life, office-based dermatology.
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Algorithms -
Aminoquinolines - therapeutic use
Antineoplastic Agents - therapeutic use
Combined Modality Therapy -
Cryotherapy -
Disease Progression -
Humans -
Imiquimod -
Keratosis, Actinic - diagnosis
Keratosis, Actinic - pathology
Keratosis, Actinic - therapy
Laser Therapy -

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Diclofenac
field cancerisation
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imiquimod
ingenol mebutate
photodynamic therapy
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