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SHR Neuro Krebs Kardio Lipid

Longhurst, HJ; Aberer, W; Bouillet, L; Caballero, T; Maurer, M; Fabien, V; Zanichelli, A; IOS Study Group.
The Icatibant Outcome Survey: treatment of laryngeal angioedema attacks.
Eur J Emerg Med. 2016; 23(3):224-227 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Autor/innen der Med Uni Graz:
Aberer Werner
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Abstract:
To characterize the management and outcomes of life-threatening laryngeal attacks of hereditary angioedema (HAE) treated with icatibant in the observational Icatibant Outcome Survey (NCT01034969) registry. This retrospective analysis was based on data from patients with HAE type I/II who received healthcare professional-administered or self-administered icatibant to treat laryngeal attacks between September 2008 and May 2013. Twenty centers in seven countries contributed data. Overall, 42 patients with HAE experienced 67 icatibant-treated laryngeal attacks. Icatibant was self-administered for 62.3% of attacks (healthcare professional-administered, 37.7%). One icatibant injection was used for 87.9% of attacks, with rescue or concomitant medication used for 9.0%. The median time to treatment was 2.0 h (n=31 attacks) and the median time to resolution was 6.0 h (n=35 attacks). This analysis describes successful use of icatibant for the treatment of laryngeal HAE attacks in a real-world setting.
Find related publications in this database (using NLM MeSH Indexing)
Angioedemas, Hereditary - drug therapy
Anti-Inflammatory Agents, Non-Steroidal - administration & dosage
Anti-Inflammatory Agents, Non-Steroidal - therapeutic use
Bradykinin - administration & dosage
Bradykinin - analogs & derivatives
Bradykinin - therapeutic use
Female -
Hereditary Angioedema Types I and II - drug therapy
Humans -
Injections, Subcutaneous -
Laryngeal Diseases - drug therapy
Male -
Retrospective Studies -
Surveys and Questionnaires -
Treatment Outcome -

Find related publications in this database (Keywords)
acquired angioedema
C1-inhibitor deficiency
hereditary angioedema
icatibant
laryngeal edema
observational study
therapy
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