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SHR Neuro Krebs Kardio Lipid

Böckle, BC; Jara, D; Nindl, W; Aberer, W; Sepp, NT.
Adrenal insufficiency as a result of long-term misuse of topical corticosteroids.
Dermatology. 2014; 228(4):289-293 (- Case Report)
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Autor/innen der Med Uni Graz:
Aberer Werner
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Abstract:
The treatment of chronic inflammatory skin disease is associated with the use of topical corticosteroids. Their efficacy, tolerability and adverse effects depend on several factors, specifically potency, type of preparation, extemporaneous dilutions, quantity used, magnitude of the treated body surface, frequency of application, location, patient age, method of application and condition of the skin barrier. We report on two men suffering from chronic inflammatory skin disease, who presented with fatigue and cushingoid appearance after prolonged self-application of potent corticosteroids. Impairment of the skin barrier due to their underlying skin disease, frequent self-application of topical steroids and repeated application of the entire body led to extensive absorption of these substances, eventually culminating in the suppression of the pituitary-hypothalamic-adrenal axis. In conclusion, topical corticosteroids are effective and well-established therapeutic modalities. However, inappropriate use of topical corticosteroids can cause side effects. © 2014 S. Karger AG, Basel
Find related publications in this database (using NLM MeSH Indexing)
Administration, Cutaneous -
Adrenal Insufficiency - chemically induced
Adult -
Betamethasone - administration & dosage
Betamethasone - adverse effects
Betamethasone - analogs & derivatives
Chronic Disease -
Cushing Syndrome - chemically induced
Dermatitis, Atopic - drug therapy
Glucocorticoids - administration & dosage
Glucocorticoids - adverse effects
Humans -
Male -
Psoriasis - drug therapy
Self Medication - adverse effects
Time Factors -
Young Adult -

Find related publications in this database (Keywords)
Adrenal insufficiency
Long-term misuse
Topical corticosteroids
Psoriasis vulgaris
Atopic dermatitis
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