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Strohmeier, B; Aberer, W; Bokanovic, D; Komericki, P; Sturm, GJ.
Simultaneous intradermal testing with hymenoptera venoms is safe and more efficient than sequential testing.
Allergy. 2013; 68(4):542-544 [OPEN ACCESS]
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Autor/innen der Med Uni Graz:
Aberer Werner
Bokanovic Danijela
Komericki Peter
Sturm Gunter

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Plum Analytics:
Background According to current guidelines, skin testing for hymenoptera venom allergy should be performed in a stepwise manner, maintaining 15- to 20-min intervals between the injections of venom. Given the long-winded procedure of sequential skin testing, we retrospectively explored the safety of simultaneous intradermal testing. Methods Four hundred and seventy-eight consecutive patients with a convincing history of an anaphylactic reaction after a hymenoptera sting were tested. All venom concentrations (0.02ml of 0.001, 0.01, 0.1, and 1.0g/ml of honey bee and wasp venom) were administered simultaneously to the skin. Results Four hundred and seventy-two (98.7%) patients tolerated the simultaneous intradermal test without any side-effects. Only three subjects (0.6%) had a presumed allergic reaction during the test; another three reactions were considered vasovagal. Conclusion Our skin test protocol with four simultaneously injected concentrations of two hymenoptera venoms is safe and permits the investigator to draw rapid conclusions about the individual's sensitization pattern.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Allergens - administration & dosage Allergens - diagnostic use
Anaphylaxis - immunology
Animals -
Arthropod Venoms - administration & dosage Arthropod Venoms - diagnostic use
Female -
Humans -
Hymenoptera - immunology
Hypersensitivity, Immediate - diagnosis
Intradermal Tests - adverse effects
Male -
Middle Aged -
Skin Tests - adverse effects Skin Tests - methods

Find related publications in this database (Keywords)
hymenoptera venom allergy
intradermal test
skin test
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