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SHR Neuro Krebs Kardio Lipid

Friedrich, G; Dikkers, FG; Arens, C; Remacle, M; Hess, M; Giovanni, A; Duflo, S; Hantzakos, A; Bachy, V; Gugatschka, M; European Laryngological Society. Phonosurgery Committee.
Vocal fold scars: current concepts and future directions. Consensus report of the Phonosurgery Committee of the European Laryngological Society.
Eur Arch Otorhinolaryngol. 2013; 270(9):2491-2507
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Autor/innen der Med Uni Graz:
Friedrich Gerhard
Gugatschka Markus
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Abstract:
Scarring of the vocal folds leads to a deterioration of the highly complex micro-structure with consecutively impaired vibratory pattern and glottic insufficiency. The resulting dysphonia is predominantly characterized by a reduced vocal capacity. Despite the considerable progress in understanding of the underlying pathophysiology, the treatment of scarred vocal folds is still an unresolved chapter in laryngology and phonosurgery. Essential for a successful treatment is an individual, multi-dimensional concept that comprises the whole armamentarium of surgical and non-surgical (i.p. voice therapy) modalities. An ideal approach would be to soften the scar, because the reduced pliability and consequently the increased vibratory rigidity impede the easiness of vibration. The chosen phonosurgical method is determined by the main clinical feature: Medialization techniques for the treatment of glottic gap, or epithelium freeing techniques for improvement of vibration characteristics often combined with injection augmentation or implantation. In severe cases, buccal mucosa grafting can be an option. New developments, include treatment with anxiolytic lasers, laser technology with ultrafine excision/ablation properties avoiding coagulation (Picosecond infrared laser, PIRL), or techniques of tissue engineering. However, despite the promising results by in vitro experiments, animal studies and first clinical trials, the step into clinical routine application has yet to be taken.
Find related publications in this database (using NLM MeSH Indexing)
Cicatrix - physiopathology
Humans -
Otolaryngology - methods
Vocal Cords - injuries
Voice Disorders - etiology

Find related publications in this database (Keywords)
Phonosurgery
Vocal fold scars
Sulcus vocalis
Vergeture
Vocal fold medialization
Micro-flap technique
Buccal mucosa grafting
Laser
Tissue engineering
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