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SHR Neuro Krebs Kardio Lipid

Stab, D; Bollmanna, S; Langkammer, C; Bredies, K; Barth, M; .
Accelerated mapping of magnetic susceptibility using 3D planes-on-apaddlewheel (POP) EPI at ultra-high field strength.
NMR BIOMED. 2017; 30(4): e3620
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Autor/innen der Med Uni Graz:
Langkammer Christian
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Abstract:
With the advent of ultra-high field MRI scanners in clinical research, susceptibility based MRI has recently gained increasing interest because of its potential to assess subtle tissue changes underlying neurological pathologies/disorders. Conventional, but rather slow, three-dimensional (3D) spoiled gradient-echo (GRE) sequences are typically employed to assess the susceptibility of tissue. 3D echo-planar imaging (EPI) represents a fast alternative but generally comes with echo-time restrictions, geometrical distortions and signal dropouts that can become severe at ultra-high fields. In this work we assess quantitative susceptibility mapping (QSM) at 7 T using non-Cartesian 3D EPI with a planeson-a-paddlewheel (POP) trajectory, which is created by rotating a standard EPI readout train around its own phase encoding axis. We show that the threefold accelerated non-Cartesian 3D POP EPI sequence enables very fast, whole brain susceptibility mapping at an isotropic resolution of 1mm and that the high image quality has sufficient signal-to-noise ratio in the phase data for reliable QSM processing. The susceptibility maps obtained were comparable with regard to QSM values and geometric distortions to those calculated from a conventional 4 min 3D GRE scan using the same QSM processing pipeline. Copyright (C) 2016 John Wiley & Sons, Ltd.

Find related publications in this database (Keywords)
brain
EPI
non-Cartesian
ultra-high field
radial
QSM
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