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SHR Neuro Krebs Kardio Lipid

Matterberger, C; Baik-Schneditz, N; Schwaberger, B; Schmölzer, GM; Mileder, L; Pichler-Stachl, E; Urlesberger, B; Pichler, G.
Blood Glucose and Cerebral Tissue Oxygenation Immediately after Birth-An Observational Study.
J Pediatr. 2018; 200(10):19-23
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Autor/innen der Med Uni Graz:
Baik-Schneditz Nariae
Mattersberger Christian
Mileder Lukas Peter
Pichler Gerhard
Pichler-Stachl Elisabeth
Schmoelzer Georg
Schwaberger Bernhard
Urlesberger Berndt
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Abstract:
To assess a possible association of blood glucose concentration with cerebral regional oxygen saturation (crSO2) and cerebral fractional tissue oxygen extraction (cFTOE) in neonates born at term and preterm 15 minutes after birth. A post-hoc analysis of secondary outcome measures of 2 prospective observational studies was performed. Neonates born at term and preterm via cesarean delivery were included if cerebral near-infrared spectroscopy measurements were performed during the immediate transition after birth and blood glucose concentrations were measured at 15-20 minutes after birth. Arterial oxygen saturation and heart rate were measured with pulse oximetry. cFTOE was calculated from arterial oxygen saturation and crSO2 values. crSO2 and cFTOE 15 minutes after birth were correlated with blood glucose concentrations. Seventy-five infants were included. In 50 neonates born at term, crSO2 and cFTOE 15 minutes after birth were 83 ± 7.7% and 0.14 ± 0.08, respectively. In 25 neonates born preterm, crSO2 and cFTOE 15 minutes after birth were 80.2 ± 12.1%, and 0.15 ± 0.1, respectively. crSO2 and cFTOE correlated significantly with blood glucose concentrations in neonates born at term and preterm. Increasing blood glucose concentrations were associated with decreasing crSO2 in neonates born at term (q = -0.35, P = .01) and neonates born preterm (q = -0.69, P = .01) and with increasing cFTOE in neonates born at term (q = 0.31, P = .03) and neonates born preterm (q = 0.67, P = .01). Blood glucose concentration was associated with cerebral oxygenation during the immediate transition after birth in neonates born at term and preterm. Copyright © 2018 Elsevier Inc. All rights reserved.

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