Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

Logo MUG-Forschungsportal

Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid

Weber, P; Nasseri, SA; Pabst, BM; Torvisco, A; Müller, P; Paschke, E; Tschernutter, M; Windischhofer, W; Withers, SG; Wrodnigg, TM; Stütz, AE.
Potent GH20 N-Acetyl-β-d-hexosaminidase Inhibitors: N-Substituted 3-acetamido-4-amino-5-hydroxymethyl-cyclopentanediols.
Molecules. 2018; 23(3): 708 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Autor/innen der Med Uni Graz:
Pabst Bettina
Paschke Eduard
Tschernutter Marion
Windischhofer Werner
Altmetrics:

Dimensions Citations:

Plum Analytics:
Number of Figures: 4
| | | |
Abstract:
From 1,2;3,4-di-O-isopropylidene-d-galactopyranose, a preliminary series of highly functionalized amino(hydroxymethyl)cyclopentanes was easily available. These amine-containing basic carbasugars featuring the d-galacto configuration are potent inhibitors of the GH20 β-d-hexosaminidases probed and may bear potential as regulators of N-acetyl-d-hexosaminidase activities in vivo.

Find related publications in this database (Keywords)
aminocyclopentane
N-acetyl-D-hexosaminidase inhibitor
Tay-Sachs
© Meduni Graz Impressum