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SHR Neuro Krebs Kardio Lipid

Mieli-Vergani, G; Vergani, D; Baumann, U; Czubkowski, P; Debray, D; Dezsofi, A; Fischler, B; Gupte, G; Hierro, L; Indolfi, G; Jahnel, J; Smets, F; Verkade, HJ; Hadžić, N.
Diagnosis and Management of Pediatric Autoimmune Liver Disease: ESPGHAN Hepatology Committee Position Statement.
J Pediatr Gastroenterol Nutr. 2018; 66(2):345-360
Web of Science PubMed FullText FullText_MUG

 

Autor/innen der Med Uni Graz:
Jahnel Jörg
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Abstract:
Paediatric autoimmune liver disease is characterized by inflammatory liver histology, circulating autoantibodies, and increased levels of IgG, in the absence of a known etiology. Three conditions have a likely autoimmune pathogenesis: autoimmune hepatitis (AIH), autoimmune sclerosing cholangitis, and de novo AIH after liver transplantation. Two types of pediatric AIH are recognized according to seropositivity for smooth muscle and/or antinuclear antibody (AIH-1) or liver kidney microsomal type 1 and/or anti-liver cytosol type 1 antibodies (AIH-2).Pertinent issues addressing the diagnosis, treatment, and long-term follow-up were formulated by a core group of ESPGHAN members. They have commissioned the first authors with execution of this project. Initially, they have performed a systematic literature search on MEDLINE, ResearchGate, and Mendeley databases during the last 30 years and produced a document focusing on prospective and retrospective studies in children. The ESPGHAN core group and ESPGHAN Hepatology Committee members voted on each recommendation, using a formal voting technique.

Find related publications in this database (Keywords)
autoimmune hepatitis
autoimmune liver disease
autoimmune sclerosing cholangitis
children
pediatric
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