Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

Logo MUG-Forschungsportal

Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid

Koestenberger, M; Nage, B; Ravekes, W; Avian, A; Burmas, A; Grangl, G; Cvirn, G; Gamillscheg, A.
Right Ventricular Outflow Tract Velocity Time Integral Determination in 570 Healthy Children and in 52 Pediatric Atrial Septal Defect Patients.
Pediatr Cardiol. 2015; 36(6):1129-1134
Web of Science PubMed FullText FullText_MUG


Autor/innen der Med Uni Graz:
Avian Alexander
Burmas Ante
Cvirn Gerhard
Gamillscheg Andreas
Grangl Gernot
Köstenberger Martin

Dimensions Citations:

Plum Analytics:
Determination of the right ventricular outflow tract velocity time integral (RVOT VTI) is an important part of the noninvasive investigation of pulmonary blood flow in adults; however, age-related pediatric reference data are lacking. We examined growth-related changes of RVOT VTI values in children and the predictive value of RVOT VTI values in identifying enhanced pulmonary blood flow in children with secundum type atrial septal defect (ASD). A prospective study was conducted in a group of 570 healthy children and 52 children with a moderate-sized to large ASD. We determined the effects of age, body length (BL), body weight (BW), and body surface area (BSA) on RVOT VTI values. The predictive value of normal values stratified for age, BW, BL, and BSA was tested in our 52 ASD children. RVOT VTI values ranged from mean 9.7 ± 1.2 cm in neonates to 23.3 ± 2.7 cm in children with 18 years of age and showed a positive correlation with age, BL, BSA, and BW. In our population, RVOT VTI z-scores showed a high specificity for detecting ASD patients (>97 %) with sensitivity up to 71 %. We provide normal ranges and calculated z-scores of pediatric RVOT VTI values. Normal RVOT VTI z-scores might be additional predictors in identifying increased pulmonary blood flow in patients with ASD.
Find related publications in this database (using NLM MeSH Indexing)
Adolescent -
Age Factors -
Blood Flow Velocity - physiology
Body Height - physiology
Body Surface Area -
Body Weight - physiology
Child -
Child, Preschool -
Female -
Heart Septal Defects, Atrial - physiopathology
Heart Ventricles - physiopathology
Hemodynamics - physiology
Humans -
Infant -
Infant, Newborn -
Male -
Predictive Value of Tests -
Prospective Studies -
Time Factors -

Find related publications in this database (Keywords)
Atrial septal defect
Pulmonary blood flow
Right ventricular outflow tract
Velocity time integral
© Meduni Graz Impressum