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Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid

Rosenmayr, A; Pointner-Prager, M; Mitterschiffthaler, A; Bozic, L; Pelzmann, B; Tüchler, H; Fae, I; Fischer, GF; Greinix, HT; Peters, Ch; Kalhs, P; Krieger, O; Linkesch, W; Nachbaur, D; Urban, Ch; Posch, U; Lanzer, G; Gabriel, Ch; Schennach, H; Mayr, WR.
What are a patient's current chances of finding a matched unrelated donor? Twenty years' central search experience in a small country.
Bone Marrow Transplant. 2012; 47(2):172-180 [OPEN ACCESS]
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Autor/innen der Med Uni Graz:
Gabriel Christian
Greinix Hildegard
Lanzer Gerhard
Linkesch Werner
Posch Ursula
Urban Ernst-Christian
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Abstract:
Between 1988 and 2007, international searches for matched unrelated donors (MUDs) were performed for 1586 Austrian patients. Between 2004 and 2007, a MUD was identified for 76.7% of the patients. Between 1996 and 2003, a donor was identified for 71.3% of the patients, and between 1988 and 1995, only for 53.4% of the patients. Search times of successful searches decreased from 7.7 months in the first period to 1.7 months in the period from 2004 to 2007. However, transplants were not performed in all cases in which a donor was found: only in 61.6% of the patients between 2004 and 2007, in 53.4% between 1996 and 2003 and in 29.6% between 1988 and 1995. Multivariate analysis determined that having a common HLA type was the most important variable impacting on finding a MUD for a patient. Factors that most strongly influence a patient's access to transplant were the patient's European origin and a short time between diagnosis and start of donor search. The strongest factor for both finding a donor and being transplanted was a search being performed during more recent years: patients' chances increased from year to year.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Adult -
Child -
Female -
HLA Antigens - genetics HLA Antigens - immunology
Hematopoietic Stem Cell Transplantation - methods
Humans -
Living Donors - statistics & numerical data Living Donors - supply & distribution
Male -
Middle Aged -
Phenotype -
Tissue and Organ Procurement - methods
Unrelated Donors - statistics & numerical data Unrelated Donors - supply & distribution

Find related publications in this database (Keywords)
matched unrelated donor
MUD
international donor search
HLA phenotypes
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