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SHR Neuro Krebs Kardio Lipid

Worel, N; Buser, A; Greinix, HT; Hägglund, H; Navarro, W; Pulsipher, MA; Nicoloso de Faveri, G; Bengtsson, M; Billen, A; Espino, G; Fechter, M; Giudice, V; Hölig, K; Kanamori, H; Kodera, Y; Leitner, G; Netelenbos, T; Niederwieser, D; van Walraven, SM; Rocha, V; Torosian, T; Vergueiro, C; Weisdorf, D; Yabe, H; Halter, JP.
Suitability Criteria for Adult Related Donors: A Consensus Statement from the Worldwide Network for Blood and Marrow Transplantation Standing Committee on Donor Issues.
Biol Blood Marrow Transplant. 2015; 21(12):2052-2060 [OPEN ACCESS]
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Autor/innen der Med Uni Graz:
Greinix Hildegard
Leitner Gerhard
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Abstract:
The number of allogeneic hematopoietic stem cell (HSC) transplants performed globally each year continues to increase. Advances in HLA typing, better supportive care, and administration of reduced-intensity conditioning regimens allow treatment of older patients with older sibling donors. Pretransplant donor assessment and testing are very important processes affecting the quality and safety of donation. For unrelated HSC donors detailed recommendations for health assessment have been published, allowing donation only if they are unrestrictedly healthy. Eligibility criteria for related donors are less strict and vary significantly between centers. In situations where a family donor does not meet the suitability criteria for unrelated donors, involved physicians often struggle with the decision whether the matched relative is suitable for donation or not. On behalf of the Worldwide Network for Blood and Marrow Transplantation Standing Committee on Donor Issues, we intended to develop a consensus document with recommendations for donor workup and final clearance of family donors who would not be able to serve as unrelated donors because of their age or pre-existing diseases. This article covers different topics intending to support decision-making, with the goal of minimizing medical risk to the donor and protection of the recipient from transmissible diseases. Copyright © 2015 American Society for Blood and Marrow Transplantation. Published by Elsevier Inc. All rights reserved.
Find related publications in this database (using NLM MeSH Indexing)
Advisory Committees -
Age Factors -
Bone Marrow Transplantation - methods
Clinical Decision-Making - ethics
Consensus -
Health Status -
Hematologic Neoplasms - immunology
Hematologic Neoplasms - pathology
Hematologic Neoplasms - therapy
Hematopoietic Stem Cell Transplantation - methods
Histocompatibility Testing -
Humans -
Informed Consent -
International Cooperation -
Risk -
Siblings -
Transplantation Conditioning -
Transplantation, Homologous -
Unrelated Donors -

Find related publications in this database (Keywords)
Related stem cell donor
Suitability criteria
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