Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

Logo MUG-Forschungsportal

Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid

Schotten, U; Hatem, S; Ravens, U; Jaïs, P; Müller, FU; Goette, A; Rohr, S; Antoons, G; Pieske, B; Scherr, D; Oto, A; Casadei, B; Verheule, S; Cartlidge, D; Steinmeyer, K; Götsche, T; Dobrev, D; Kockskämper, J; Lendeckel, U; Fabritz, L; Kirchhof, P; Camm, AJ; EUTRAF investigators.
The European Network for Translational Research in Atrial Fibrillation (EUTRAF): objectives and initial results.
Europace. 2015; 17(10):1457-1466 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Autor/innen der Med Uni Graz:
Antoons Gudrun
Pieske Burkert Mathias
Scherr Daniel
Altmetrics:

Dimensions Citations:

Plum Analytics:
Abstract:
Atrial fibrillation (AF) is the most common sustained arrhythmia in the general population. As an age-related arrhythmia AF is becoming a huge socio-economic burden for European healthcare systems. Despite significant progress in our understanding of the pathophysiology of AF, therapeutic strategies for AF have not changed substantially and the major challenges in the management of AF are still unmet. This lack of progress may be related to the multifactorial pathogenesis of atrial remodelling and AF that hampers the identification of causative pathophysiological alterations in individual patients. Also, again new mechanisms have been identified and the relative contribution of these mechanisms still has to be established. In November 2010, the European Union launched the large collaborative project EUTRAF (European Network of Translational Research in Atrial Fibrillation) to address these challenges. The main aims of EUTRAF are to study the main mechanisms of initiation and perpetuation of AF, to identify the molecular alterations underlying atrial remodelling, to develop markers allowing to monitor this processes, and suggest strategies to treat AF based on insights in newly defined disease mechanisms. This article reports on the objectives, the structure, and initial results of this network. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2015. For permissions please email: journals.permissions@oup.com.
Find related publications in this database (using NLM MeSH Indexing)
Atrial Fibrillation - diagnosis Atrial Fibrillation - genetics Atrial Fibrillation - physiopathology
Atrial Remodeling -
Cooperative Behavior -
Electrocardiography -
Electrocardiography -
Humans -
Translational Medical Research - trends

Find related publications in this database (Keywords)
Atrial fibrillation
Pathophysiology
Atrial remodelling
Stroke
Biomarker
Diagnostic tools
© Meduni Graz Impressum